Product Data Sheet
VU 0364739 hydrochloride
Catalog No. A77146
VU 0364739 hydrochloride is a selective inhibitor of phospholipase D2 (PLD2), exhibiting an IC50 of 20 nM for PLD2 while having significantly lower activity against PLD1 (IC50 of 1500 nM). This compound has been shown to induce apoptosis, making it a valuable reagent for cancer research. Its specificity and potent biological activity position VU 0364739 as an important tool for studying PLD2's role in cellular processes and cancer pathophysiology.
Chemical Information
| Catalog Num | A77146 |
|---|---|
| M. Wt | 482.98 |
| Formula | C26H28ClFN4O2 |
| Purity | >98% |
| Storage | at -20 °C 3 years (powder form); at -20 °C 6 months (Solution base) |
| CAS No. | 1244640-48-9 |
| Synonyms | |
| SMILES | O=C(C1=CC=C2C=CC=CC2=C1)NCCN(CC3)CCC3(N(C4=CC=CC(F)=C4)CN5)C5=O.[H]Cl |
Biological Activity
| Description | VU 0364739 hydrochloride is a selective inhibitor of phospholipase D2 (PLD2), exhibiting an IC50 of 20 nM for PLD2 while having significantly lower activity against PLD1 (IC50 of 1500 nM). This compound has been shown to induce apoptosis, making it a valuable reagent for cancer research. Its specificity and potent biological activity position VU 0364739 as an important tool for studying PLD2's role in cellular processes and cancer pathophysiology. |
|---|
RETURN POLICY
Adooq’s Unconditional Return Policy ensures a smooth online shopping experience for our customers. If you are in any way unsatisfied with your purchase, you may return any item(s) within 7 days of receiving it. In the event of product quality issues, either protocol related or product related problems, you may return any item(s) within 365 days from the original purchase date. Please follow the instructions below when returning products.
Adooq’s Unconditional Return Policy ensures a smooth online shopping experience for our customers. If you are in any way unsatisfied with your purchase, you may return any item(s) within 7 days of receiving it. In the event of product quality issues, either protocol related or product related problems, you may return any item(s) within 365 days from the original purchase date. Please follow the instructions below when returning products.
SHIPPING AND STORAGE
Adooq products are transported at room temperature. If you receive the product at room temperature, please rest assured, the Adooq Quality Inspection Department has conducted experiments to verify that the normal temperature placement of one month will not affect the biological activity of powder products. After collecting, please store the product according to the requirements described in the datasheet. Most Adooq products are stable under the recommended conditions.
Adooq products are transported at room temperature. If you receive the product at room temperature, please rest assured, the Adooq Quality Inspection Department has conducted experiments to verify that the normal temperature placement of one month will not affect the biological activity of powder products. After collecting, please store the product according to the requirements described in the datasheet. Most Adooq products are stable under the recommended conditions.
