Product Data Sheet
ROC-0929
Catalog No. A77147
ROC-0929 is a potent and selective inhibitor of secreted phospholipases A2 (sPLA2s), specifically targeting hGX with an IC50 of 80 nM. By inhibiting the phosphorylation of ERK1/2 and p-38, ROC-0929 demonstrates significant anti-inflammatory activity. This compound holds promise for investigating the role of sPLA2s in inflammation-related diseases, making it a valuable tool for research in this area.
Chemical Information
| Catalog Num | A77147 |
|---|---|
| M. Wt | 561.65 |
| Formula | C30H31N3O6S |
| Purity | >98% |
| Storage | at -20 °C 3 years (powder form); at -20 °C 6 months (Solution base) |
| CAS No. | 1048660-43-0 |
| Synonyms | |
| SMILES | O=C(C(N)=O)C1=C(CC(C)C)N(CC2=CC=CC=C2)C3=CC=CC(OC(C)C(NS(=O)(C4=CC=CC=C4)=O)=O)=C31 |
Biological Activity
| Description | ROC-0929 is a potent and selective inhibitor of secreted phospholipases A2 (sPLA2s), specifically targeting hGX with an IC50 of 80 nM. By inhibiting the phosphorylation of ERK1/2 and p-38, ROC-0929 demonstrates significant anti-inflammatory activity. This compound holds promise for investigating the role of sPLA2s in inflammation-related diseases, making it a valuable tool for research in this area. |
|---|
RETURN POLICY
Adooq’s Unconditional Return Policy ensures a smooth online shopping experience for our customers. If you are in any way unsatisfied with your purchase, you may return any item(s) within 7 days of receiving it. In the event of product quality issues, either protocol related or product related problems, you may return any item(s) within 365 days from the original purchase date. Please follow the instructions below when returning products.
Adooq’s Unconditional Return Policy ensures a smooth online shopping experience for our customers. If you are in any way unsatisfied with your purchase, you may return any item(s) within 7 days of receiving it. In the event of product quality issues, either protocol related or product related problems, you may return any item(s) within 365 days from the original purchase date. Please follow the instructions below when returning products.
SHIPPING AND STORAGE
Adooq products are transported at room temperature. If you receive the product at room temperature, please rest assured, the Adooq Quality Inspection Department has conducted experiments to verify that the normal temperature placement of one month will not affect the biological activity of powder products. After collecting, please store the product according to the requirements described in the datasheet. Most Adooq products are stable under the recommended conditions.
Adooq products are transported at room temperature. If you receive the product at room temperature, please rest assured, the Adooq Quality Inspection Department has conducted experiments to verify that the normal temperature placement of one month will not affect the biological activity of powder products. After collecting, please store the product according to the requirements described in the datasheet. Most Adooq products are stable under the recommended conditions.
