Product Data Sheet

AGN-190383

Catalog No. A77177

main product photo
AGN-190383 is a potent inhibitor of bee venom phospholipase A2, targeting key enzymes involved in inflammatory processes. It effectively inhibits both hormone-operated and depolarization-dependent calcium mobilization, as well as fMLP-stimulated increases in free cytosolic calcium levels. Due to its ability to modulate calcium signaling and exhibit anti-inflammatory activity, AGN-190383 is valuable for research applications in studying inflammation and calcium-related cellular responses.
Chemical Information
Catalog NumA77177
M. Wt340.45
FormulaC19H32O5
Purity>98%
Storageat -20 °C 3 years (powder form); at -20 °C 6 months (Solution base)
CAS No.120755-15-9
Synonyms
SMILESO=C1OC(C(C(CCCCCCCCCCCC)OC(C)=O)=C1)O
Biological Activity
DescriptionAGN-190383 is a potent inhibitor of bee venom phospholipase A2, targeting key enzymes involved in inflammatory processes. It effectively inhibits both hormone-operated and depolarization-dependent calcium mobilization, as well as fMLP-stimulated increases in free cytosolic calcium levels. Due to its ability to modulate calcium signaling and exhibit anti-inflammatory activity, AGN-190383 is valuable for research applications in studying inflammation and calcium-related cellular responses.
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