Product Data Sheet
ML114
Catalog No. A77180
ML114 is a selective inhibitor of the serine hydrolase RBBP9, exhibiting an IC50 of 0.63 μM against recombinant RBBP9. This compound has been shown to suppress the proliferation of human pluripotent stem cells (hPSCs) by modulating the expression of NFYA and other associated factors, without triggering differentiation. ML114 is valuable for research in cancer pathology, particularly in the study of retinoblastoma.
Chemical Information
| Catalog Num | A77180 |
|---|---|
| M. Wt | 252.33 |
| Formula | C12H16N2O2S |
| Purity | >98% |
| Storage | at -20 °C 3 years (powder form); at -20 °C 6 months (Solution base) |
| CAS No. | 866149-26-0 |
| Synonyms | |
| SMILES | C/C(C1=NC=CS1)=N\OC(C2CCCCC2)=O |
Biological Activity
| Description | ML114 is a selective inhibitor of the serine hydrolase RBBP9, exhibiting an IC50 of 0.63 μM against recombinant RBBP9. This compound has been shown to suppress the proliferation of human pluripotent stem cells (hPSCs) by modulating the expression of NFYA and other associated factors, without triggering differentiation. ML114 is valuable for research in cancer pathology, particularly in the study of retinoblastoma. |
|---|
RETURN POLICY
Adooq’s Unconditional Return Policy ensures a smooth online shopping experience for our customers. If you are in any way unsatisfied with your purchase, you may return any item(s) within 7 days of receiving it. In the event of product quality issues, either protocol related or product related problems, you may return any item(s) within 365 days from the original purchase date. Please follow the instructions below when returning products.
Adooq’s Unconditional Return Policy ensures a smooth online shopping experience for our customers. If you are in any way unsatisfied with your purchase, you may return any item(s) within 7 days of receiving it. In the event of product quality issues, either protocol related or product related problems, you may return any item(s) within 365 days from the original purchase date. Please follow the instructions below when returning products.
SHIPPING AND STORAGE
Adooq products are transported at room temperature. If you receive the product at room temperature, please rest assured, the Adooq Quality Inspection Department has conducted experiments to verify that the normal temperature placement of one month will not affect the biological activity of powder products. After collecting, please store the product according to the requirements described in the datasheet. Most Adooq products are stable under the recommended conditions.
Adooq products are transported at room temperature. If you receive the product at room temperature, please rest assured, the Adooq Quality Inspection Department has conducted experiments to verify that the normal temperature placement of one month will not affect the biological activity of powder products. After collecting, please store the product according to the requirements described in the datasheet. Most Adooq products are stable under the recommended conditions.
