Product Data Sheet
sPLA2-IIA Inhibitor
Catalog No. A77181
sPLA2-IIA Inhibitor is a cyclic pentapeptide analog of FLSYK, specifically designed to target human Group IIA phospholipase A2 (hGIIA). This compound effectively binds to hGIIA, inhibiting its enzymatic activity and preventing the hydrolysis of glycerophospholipids. This inhibition leads to decreased production of free fatty acids, such as arachidonic acid, making it a valuable tool for studying inflammatory processes and lipid metabolism in various biological models. Its application is particularly relevant in research aimed at understanding related pathophysiological conditions.
Chemical Information
| Catalog Num | A77181 |
|---|---|
| M. Wt | 750.89 |
| Formula | C41H50N8O6 |
| Purity | >98% |
| Storage | at -20 °C 3 years (powder form); at -20 °C 6 months (Solution base) |
| CAS No. | 236394-37-9 |
| Synonyms | |
| SMILES | C(C1=CC2=C(C=C1)C=CC=C2)[C@@H]3NC(=O)[C@H](CCCNC(=N)N)NC(=O)[C@H](CC4=CC5=C(C=C4)C=CC=C5)NC(=O)[C@H](CO)NC(=O)[C@H](CC(C)C)NC3=O |
Biological Activity
| Description | sPLA2-IIA Inhibitor is a cyclic pentapeptide analog of FLSYK, specifically designed to target human Group IIA phospholipase A2 (hGIIA). This compound effectively binds to hGIIA, inhibiting its enzymatic activity and preventing the hydrolysis of glycerophospholipids. This inhibition leads to decreased production of free fatty acids, such as arachidonic acid, making it a valuable tool for studying inflammatory processes and lipid metabolism in various biological models. Its application is particularly relevant in research aimed at understanding related pathophysiological conditions. |
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RETURN POLICY
Adooq’s Unconditional Return Policy ensures a smooth online shopping experience for our customers. If you are in any way unsatisfied with your purchase, you may return any item(s) within 7 days of receiving it. In the event of product quality issues, either protocol related or product related problems, you may return any item(s) within 365 days from the original purchase date. Please follow the instructions below when returning products.
Adooq’s Unconditional Return Policy ensures a smooth online shopping experience for our customers. If you are in any way unsatisfied with your purchase, you may return any item(s) within 7 days of receiving it. In the event of product quality issues, either protocol related or product related problems, you may return any item(s) within 365 days from the original purchase date. Please follow the instructions below when returning products.
SHIPPING AND STORAGE
Adooq products are transported at room temperature. If you receive the product at room temperature, please rest assured, the Adooq Quality Inspection Department has conducted experiments to verify that the normal temperature placement of one month will not affect the biological activity of powder products. After collecting, please store the product according to the requirements described in the datasheet. Most Adooq products are stable under the recommended conditions.
Adooq products are transported at room temperature. If you receive the product at room temperature, please rest assured, the Adooq Quality Inspection Department has conducted experiments to verify that the normal temperature placement of one month will not affect the biological activity of powder products. After collecting, please store the product according to the requirements described in the datasheet. Most Adooq products are stable under the recommended conditions.
