Product Data Sheet
AK106-001616
Catalog No. A77214
AK106-001616 is a selective inhibitor of cytosolic phospholipase A2 (cPLA2), exhibiting a potent inhibition with an IC50 of 3.8 nmol/L. This compound effectively reduces the synthesis of pro-inflammatory mediators, including prostaglandins E2 and leukotrienes B4, in stimulated cells. AK106-001616 is valuable for research into inflammatory diseases, neuropathic pain, and pulmonary fibrosis, providing insights into the modulation of inflammatory pathways.
Chemical Information
| Catalog Num | A77214 |
|---|---|
| M. Wt | 427.50 |
| Formula | C26H25N3O3 |
| Purity | >98% |
| Storage | at -20 °C 3 years (powder form); at -20 °C 6 months (Solution base) |
| CAS No. | 590416-75-4 |
| Synonyms | |
| SMILES | O=C(O)CCC1=CC(C2=CC3=C(N(C)N=C3)C=C2)=C(OC4CC5=C(C=CC=C5)C4)C(N)=C1 |
Biological Activity
| Description | AK106-001616 is a selective inhibitor of cytosolic phospholipase A2 (cPLA2), exhibiting a potent inhibition with an IC50 of 3.8 nmol/L. This compound effectively reduces the synthesis of pro-inflammatory mediators, including prostaglandins E2 and leukotrienes B4, in stimulated cells. AK106-001616 is valuable for research into inflammatory diseases, neuropathic pain, and pulmonary fibrosis, providing insights into the modulation of inflammatory pathways. |
|---|
RETURN POLICY
Adooq’s Unconditional Return Policy ensures a smooth online shopping experience for our customers. If you are in any way unsatisfied with your purchase, you may return any item(s) within 7 days of receiving it. In the event of product quality issues, either protocol related or product related problems, you may return any item(s) within 365 days from the original purchase date. Please follow the instructions below when returning products.
Adooq’s Unconditional Return Policy ensures a smooth online shopping experience for our customers. If you are in any way unsatisfied with your purchase, you may return any item(s) within 7 days of receiving it. In the event of product quality issues, either protocol related or product related problems, you may return any item(s) within 365 days from the original purchase date. Please follow the instructions below when returning products.
SHIPPING AND STORAGE
Adooq products are transported at room temperature. If you receive the product at room temperature, please rest assured, the Adooq Quality Inspection Department has conducted experiments to verify that the normal temperature placement of one month will not affect the biological activity of powder products. After collecting, please store the product according to the requirements described in the datasheet. Most Adooq products are stable under the recommended conditions.
Adooq products are transported at room temperature. If you receive the product at room temperature, please rest assured, the Adooq Quality Inspection Department has conducted experiments to verify that the normal temperature placement of one month will not affect the biological activity of powder products. After collecting, please store the product according to the requirements described in the datasheet. Most Adooq products are stable under the recommended conditions.
