Product Data Sheet
CGS 24592
Catalog No. A77279
CGS 24592 is a selective and potent inhibitor of neutral endopeptidase 24.11 (NEP), exhibiting an IC50 value of 1.6 nmol/L. This compound effectively decreases the degradation of atrial natriuretic peptide (ANP), leading to increased plasma levels of ANP and subsequent reduction in blood pressure. CGS 24592 is valuable for research in cardiovascular diseases, particularly in the contexts of hypertension and congestive heart failure.
Chemical Information
| Catalog Num | A77279 |
|---|---|
| M. Wt | 406.37 |
| Formula | C19H23N2O6P |
| Purity | >98% |
| Storage | at -20 °C 3 years (powder form); at -20 °C 6 months (Solution base) |
| CAS No. | 147923-04-4 |
| Synonyms | |
| SMILES | OC(CCNC([C@@H](NCP(O)(O)=O)CC1=CC=C(C2=CC=CC=C2)C=C1)=O)=O |
Biological Activity
| Description | CGS 24592 is a selective and potent inhibitor of neutral endopeptidase 24.11 (NEP), exhibiting an IC50 value of 1.6 nmol/L. This compound effectively decreases the degradation of atrial natriuretic peptide (ANP), leading to increased plasma levels of ANP and subsequent reduction in blood pressure. CGS 24592 is valuable for research in cardiovascular diseases, particularly in the contexts of hypertension and congestive heart failure. |
|---|
RETURN POLICY
Adooq’s Unconditional Return Policy ensures a smooth online shopping experience for our customers. If you are in any way unsatisfied with your purchase, you may return any item(s) within 7 days of receiving it. In the event of product quality issues, either protocol related or product related problems, you may return any item(s) within 365 days from the original purchase date. Please follow the instructions below when returning products.
Adooq’s Unconditional Return Policy ensures a smooth online shopping experience for our customers. If you are in any way unsatisfied with your purchase, you may return any item(s) within 7 days of receiving it. In the event of product quality issues, either protocol related or product related problems, you may return any item(s) within 365 days from the original purchase date. Please follow the instructions below when returning products.
SHIPPING AND STORAGE
Adooq products are transported at room temperature. If you receive the product at room temperature, please rest assured, the Adooq Quality Inspection Department has conducted experiments to verify that the normal temperature placement of one month will not affect the biological activity of powder products. After collecting, please store the product according to the requirements described in the datasheet. Most Adooq products are stable under the recommended conditions.
Adooq products are transported at room temperature. If you receive the product at room temperature, please rest assured, the Adooq Quality Inspection Department has conducted experiments to verify that the normal temperature placement of one month will not affect the biological activity of powder products. After collecting, please store the product according to the requirements described in the datasheet. Most Adooq products are stable under the recommended conditions.
