Product Data Sheet

BC-23

Catalog No. A77317

main product photo
BC-23 (NSC 45382) is a potent proteasome inhibitor that selectively inhibits the chymotrypsin-like (CT-L) activity of the proteasome complex. This compound demonstrates significant cytotoxicity against malignant cells while sparing normal cells, making it a valuable tool for cancer research. BC-23 is utilized in studies aimed at elucidating the role of proteasomal degradation in cell cycle regulation and tumor progression.
Chemical Information
Catalog NumA77317
M. Wt439.87
FormulaC21H14ClN3O4S
Purity>98%
Storageat -20 °C 3 years (powder form); at -20 °C 6 months (Solution base)
CAS No.6298-15-3
SynonymsNSC 45382
SMILESO=S(C1=CC=C(C=C1)NC(C2=O)=C(C(C3=C2C=CC=C3)=O)Cl)(NC4=NC=CC=C4)=O
Biological Activity
DescriptionBC-23 (NSC 45382) is a potent proteasome inhibitor that selectively inhibits the chymotrypsin-like (CT-L) activity of the proteasome complex. This compound demonstrates significant cytotoxicity against malignant cells while sparing normal cells, making it a valuable tool for cancer research. BC-23 is utilized in studies aimed at elucidating the role of proteasomal degradation in cell cycle regulation and tumor progression.
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SHIPPING AND STORAGE
Adooq products are transported at room temperature. If you receive the product at room temperature, please rest assured, the Adooq Quality Inspection Department has conducted experiments to verify that the normal temperature placement of one month will not affect the biological activity of powder products. After collecting, please store the product according to the requirements described in the datasheet. Most Adooq products are stable under the recommended conditions.