Product Data Sheet
Immunoproteasome inhibitor 1
Catalog No. A77324
Immunoproteasome inhibitor 1 is a potent reversible inhibitor of the immunoproteasome and the proteasome, targeting the β5c, β1i, and β5i subunits with Kis of 1.18, 0.27, and 1.91 μM, respectively. This compound exhibits significant biological activity in modulating protein degradation pathways, making it a valuable tool for investigating the role of the immunoproteasome in various neoplastic diseases. Its unique mechanism of action facilitates research into targeted therapies and mechanistic studies in oncology.
Chemical Information
| Catalog Num | A77324 |
|---|---|
| M. Wt | 358.43 |
| Formula | C20H26N2O4 |
| Purity | >98% |
| Storage | at -20 °C 3 years (powder form); at -20 °C 6 months (Solution base) |
| CAS No. | 2755772-63-3 |
| Synonyms | |
| SMILES | O=C1C2=CC(OC)=C(OC)C=C2C=CN1C/C=C/C(NCCC(C)C)=O |
Biological Activity
| Description | Immunoproteasome inhibitor 1 is a potent reversible inhibitor of the immunoproteasome and the proteasome, targeting the β5c, β1i, and β5i subunits with Kis of 1.18, 0.27, and 1.91 μM, respectively. This compound exhibits significant biological activity in modulating protein degradation pathways, making it a valuable tool for investigating the role of the immunoproteasome in various neoplastic diseases. Its unique mechanism of action facilitates research into targeted therapies and mechanistic studies in oncology. |
|---|
RETURN POLICY
Adooq’s Unconditional Return Policy ensures a smooth online shopping experience for our customers. If you are in any way unsatisfied with your purchase, you may return any item(s) within 7 days of receiving it. In the event of product quality issues, either protocol related or product related problems, you may return any item(s) within 365 days from the original purchase date. Please follow the instructions below when returning products.
Adooq’s Unconditional Return Policy ensures a smooth online shopping experience for our customers. If you are in any way unsatisfied with your purchase, you may return any item(s) within 7 days of receiving it. In the event of product quality issues, either protocol related or product related problems, you may return any item(s) within 365 days from the original purchase date. Please follow the instructions below when returning products.
SHIPPING AND STORAGE
Adooq products are transported at room temperature. If you receive the product at room temperature, please rest assured, the Adooq Quality Inspection Department has conducted experiments to verify that the normal temperature placement of one month will not affect the biological activity of powder products. After collecting, please store the product according to the requirements described in the datasheet. Most Adooq products are stable under the recommended conditions.
Adooq products are transported at room temperature. If you receive the product at room temperature, please rest assured, the Adooq Quality Inspection Department has conducted experiments to verify that the normal temperature placement of one month will not affect the biological activity of powder products. After collecting, please store the product according to the requirements described in the datasheet. Most Adooq products are stable under the recommended conditions.
