Product Data Sheet
20S Proteasome-IN-2
Catalog No. A77332
20S Proteasome-IN-2 is a selective inhibitor of the human 20S proteasome, specifically targeting the β5 subunit with an IC50 of 0.18 μM. This compound exhibits significant anti-proliferative effects in both in vitro and in vivo models, effectively inducing cell cycle arrest at the G2/M phase. It serves as a valuable tool for research focused on cancer biology and the mechanisms of proteasome function.
Chemical Information
| Catalog Num | A77332 |
|---|---|
| M. Wt | 620.76 |
| Formula | C30H44N4O8S |
| Purity | >98% |
| Storage | at -20 °C 3 years (powder form); at -20 °C 6 months (Solution base) |
| CAS No. | 2028300-31-2 |
| Synonyms | |
| SMILES | O=C(N[C@@H](COC)C(N[C@@H](CC(C)C)C(C1=CC=CO1)=O)=O)[C@@H](NS(=O)(C2=CC=C(C)C=C2)=O)CC(NCC(C)(C)C)=O |
Biological Activity
| Description | 20S Proteasome-IN-2 is a selective inhibitor of the human 20S proteasome, specifically targeting the β5 subunit with an IC50 of 0.18 μM. This compound exhibits significant anti-proliferative effects in both in vitro and in vivo models, effectively inducing cell cycle arrest at the G2/M phase. It serves as a valuable tool for research focused on cancer biology and the mechanisms of proteasome function. |
|---|
RETURN POLICY
Adooq’s Unconditional Return Policy ensures a smooth online shopping experience for our customers. If you are in any way unsatisfied with your purchase, you may return any item(s) within 7 days of receiving it. In the event of product quality issues, either protocol related or product related problems, you may return any item(s) within 365 days from the original purchase date. Please follow the instructions below when returning products.
Adooq’s Unconditional Return Policy ensures a smooth online shopping experience for our customers. If you are in any way unsatisfied with your purchase, you may return any item(s) within 7 days of receiving it. In the event of product quality issues, either protocol related or product related problems, you may return any item(s) within 365 days from the original purchase date. Please follow the instructions below when returning products.
SHIPPING AND STORAGE
Adooq products are transported at room temperature. If you receive the product at room temperature, please rest assured, the Adooq Quality Inspection Department has conducted experiments to verify that the normal temperature placement of one month will not affect the biological activity of powder products. After collecting, please store the product according to the requirements described in the datasheet. Most Adooq products are stable under the recommended conditions.
Adooq products are transported at room temperature. If you receive the product at room temperature, please rest assured, the Adooq Quality Inspection Department has conducted experiments to verify that the normal temperature placement of one month will not affect the biological activity of powder products. After collecting, please store the product according to the requirements described in the datasheet. Most Adooq products are stable under the recommended conditions.
