Product Data Sheet

A-933548

Catalog No. A77359

main product photo
A-933548 is a highly potent and selective inhibitor of calpain, demonstrating a Ki value of 18 nM. This compound's ability to modulate calpain activity makes it a valuable tool for research into neurodegenerative disorders, particularly Alzheimer's disease. Its specificity for calpain allows for detailed studies of calpain-mediated pathways and potential therapeutic interventions.
Chemical Information
Catalog NumA77359
M. Wt439.47
FormulaC25H21N5O3
Purity>98%
Storageat -20 °C 3 years (powder form); at -20 °C 6 months (Solution base)
CAS No.1037826-43-9
Synonyms
SMILESO=C(C1=C(N=CC=C1)N2N=C(C=C2)C3=CC=CC=C3)NC(CC4=CC=CC=C4)C(C(N)=O)=O
Biological Activity
DescriptionA-933548 is a highly potent and selective inhibitor of calpain, demonstrating a Ki value of 18 nM. This compound's ability to modulate calpain activity makes it a valuable tool for research into neurodegenerative disorders, particularly Alzheimer's disease. Its specificity for calpain allows for detailed studies of calpain-mediated pathways and potential therapeutic interventions.
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