Product Data Sheet
NC-002
Catalog No. A77362
NC-002 is a cell-permeable trypsin-like proteasome inhibitor that selectively targets the proteasome while sparing lysosomal cysteine proteases. This epoxyketone derivative of Leupeptin enhances the sensitivity of myeloma cells to Bortezomib and Carfilzomib, making it a valuable tool for cancer research. NC-002's unique mechanism offers potential insights into proteasome-related pathways and therapeutic strategies in oncology.
Chemical Information
| Catalog Num | A77362 |
|---|---|
| M. Wt | 482.62 |
| Formula | C23H42N6O5 |
| Purity | >98% |
| Storage | at -20 °C 3 years (powder form); at -20 °C 6 months (Solution base) |
| CAS No. | 1356828-46-0 |
| Synonyms | |
| SMILES | CC(C)C[C@H](NC(C)=O)C(N[C@@H](CC(C)C)C(N[C@@H](CCCNC(N)=N)C([C@]1(CO1)C)=O)=O)=O |
Biological Activity
| Description | NC-002 is a cell-permeable trypsin-like proteasome inhibitor that selectively targets the proteasome while sparing lysosomal cysteine proteases. This epoxyketone derivative of Leupeptin enhances the sensitivity of myeloma cells to Bortezomib and Carfilzomib, making it a valuable tool for cancer research. NC-002's unique mechanism offers potential insights into proteasome-related pathways and therapeutic strategies in oncology. |
|---|
RETURN POLICY
Adooq’s Unconditional Return Policy ensures a smooth online shopping experience for our customers. If you are in any way unsatisfied with your purchase, you may return any item(s) within 7 days of receiving it. In the event of product quality issues, either protocol related or product related problems, you may return any item(s) within 365 days from the original purchase date. Please follow the instructions below when returning products.
Adooq’s Unconditional Return Policy ensures a smooth online shopping experience for our customers. If you are in any way unsatisfied with your purchase, you may return any item(s) within 7 days of receiving it. In the event of product quality issues, either protocol related or product related problems, you may return any item(s) within 365 days from the original purchase date. Please follow the instructions below when returning products.
SHIPPING AND STORAGE
Adooq products are transported at room temperature. If you receive the product at room temperature, please rest assured, the Adooq Quality Inspection Department has conducted experiments to verify that the normal temperature placement of one month will not affect the biological activity of powder products. After collecting, please store the product according to the requirements described in the datasheet. Most Adooq products are stable under the recommended conditions.
Adooq products are transported at room temperature. If you receive the product at room temperature, please rest assured, the Adooq Quality Inspection Department has conducted experiments to verify that the normal temperature placement of one month will not affect the biological activity of powder products. After collecting, please store the product according to the requirements described in the datasheet. Most Adooq products are stable under the recommended conditions.
