Product Data Sheet
ML202
Catalog No. A77413
ML202 is a potent allosteric activator of human pyruvate kinase M2 (hPK-M2), designed to enhance the enzyme's activity by modulating the cooperativity of phosphoenolpyruvate (PEP) binding. It specifically influences the PEP binding site with minimal impact on adenosine diphosphate (ADP) binding. This compound is valuable for studying metabolic pathways and cellular energy regulation, making it a useful tool in cancer research and metabolic studies.
Chemical Information
| Catalog Num | A77413 |
|---|---|
| M. Wt | 387.48 |
| Formula | C18H17N3O3S2 |
| Purity | >98% |
| Storage | at -20 °C 3 years (powder form); at -20 °C 6 months (Solution base) |
| CAS No. | 1221186-52-2 |
| Synonyms | |
| SMILES | O=C1C2=C(C3=C(N2C)C=C(S(C)=O)S3)C=NN1CC4=CC(OC)=CC=C4 |
Biological Activity
| Description | ML202 is a potent allosteric activator of human pyruvate kinase M2 (hPK-M2), designed to enhance the enzyme's activity by modulating the cooperativity of phosphoenolpyruvate (PEP) binding. It specifically influences the PEP binding site with minimal impact on adenosine diphosphate (ADP) binding. This compound is valuable for studying metabolic pathways and cellular energy regulation, making it a useful tool in cancer research and metabolic studies. |
|---|
RETURN POLICY
Adooq’s Unconditional Return Policy ensures a smooth online shopping experience for our customers. If you are in any way unsatisfied with your purchase, you may return any item(s) within 7 days of receiving it. In the event of product quality issues, either protocol related or product related problems, you may return any item(s) within 365 days from the original purchase date. Please follow the instructions below when returning products.
Adooq’s Unconditional Return Policy ensures a smooth online shopping experience for our customers. If you are in any way unsatisfied with your purchase, you may return any item(s) within 7 days of receiving it. In the event of product quality issues, either protocol related or product related problems, you may return any item(s) within 365 days from the original purchase date. Please follow the instructions below when returning products.
SHIPPING AND STORAGE
Adooq products are transported at room temperature. If you receive the product at room temperature, please rest assured, the Adooq Quality Inspection Department has conducted experiments to verify that the normal temperature placement of one month will not affect the biological activity of powder products. After collecting, please store the product according to the requirements described in the datasheet. Most Adooq products are stable under the recommended conditions.
Adooq products are transported at room temperature. If you receive the product at room temperature, please rest assured, the Adooq Quality Inspection Department has conducted experiments to verify that the normal temperature placement of one month will not affect the biological activity of powder products. After collecting, please store the product according to the requirements described in the datasheet. Most Adooq products are stable under the recommended conditions.
