Product Data Sheet

PKR activator 5

Catalog No. A77415

main product photo
PKR Activator 5 (Compound 18) is a potent activator of pyruvate kinase R (PKR), exhibiting an AC50 of 28 nM. This compound enhances PKR activity, which plays a critical role in regulating glycolysis and energy metabolism. PKR Activator 5 is valuable for research applications aimed at understanding the metabolic pathways associated with PKR and their implications in cancer and metabolic disorders.
Chemical Information
Catalog NumA77415
M. Wt491.91
FormulaC23H19ClFN9O
Purity>98%
Storageat -20 °C 3 years (powder form); at -20 °C 6 months (Solution base)
CAS No.2761226-35-9
Synonyms
SMILESCC1=NN(C(CNC(NCC2=NC=NN2C3=CC4=C(C=C3)C=CC=N4)=O)=N1)C5=CC=C(C(F)=C5)Cl
Biological Activity
DescriptionPKR Activator 5 (Compound 18) is a potent activator of pyruvate kinase R (PKR), exhibiting an AC50 of 28 nM. This compound enhances PKR activity, which plays a critical role in regulating glycolysis and energy metabolism. PKR Activator 5 is valuable for research applications aimed at understanding the metabolic pathways associated with PKR and their implications in cancer and metabolic disorders.
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