Product Data Sheet
Mitapivat hemisulfate
Catalog No. A77418
Mitapivat hemisulfate is an orally active allosteric activator of pyruvate kinase (PK). This compound enhances enzymatic activity, improves protein stability, and elevates ATP levels across various PKLR genotypes, making it a potential therapeutic option for restoring function in PK-deficient glycolytic pathways. Mitapivat hemisulfate is suitable for research applications focused on PK deficiency and metabolic disorders.
Chemical Information
| Catalog Num | A77418 |
|---|---|
| M. Wt | 499.60 |
| Formula | C24H26N4O3S.1/2H2SO4 |
| Purity | >98% |
| Storage | at -20 °C 3 years (powder form); at -20 °C 6 months (Solution base) |
| CAS No. | 2329710-91-8 |
| Synonyms | AG-348 hemisulfate |
| SMILES | O=C(N1CCN(CC2CC2)CC1)C3=CC=C(NS(=O)(C4=CC=CC5=CC=CN=C54)=O)C=C3.O=S(O)(O)=O.[0.5] |
Biological Activity
| Description | Mitapivat hemisulfate is an orally active allosteric activator of pyruvate kinase (PK). This compound enhances enzymatic activity, improves protein stability, and elevates ATP levels across various PKLR genotypes, making it a potential therapeutic option for restoring function in PK-deficient glycolytic pathways. Mitapivat hemisulfate is suitable for research applications focused on PK deficiency and metabolic disorders. |
|---|
RETURN POLICY
Adooq’s Unconditional Return Policy ensures a smooth online shopping experience for our customers. If you are in any way unsatisfied with your purchase, you may return any item(s) within 7 days of receiving it. In the event of product quality issues, either protocol related or product related problems, you may return any item(s) within 365 days from the original purchase date. Please follow the instructions below when returning products.
Adooq’s Unconditional Return Policy ensures a smooth online shopping experience for our customers. If you are in any way unsatisfied with your purchase, you may return any item(s) within 7 days of receiving it. In the event of product quality issues, either protocol related or product related problems, you may return any item(s) within 365 days from the original purchase date. Please follow the instructions below when returning products.
SHIPPING AND STORAGE
Adooq products are transported at room temperature. If you receive the product at room temperature, please rest assured, the Adooq Quality Inspection Department has conducted experiments to verify that the normal temperature placement of one month will not affect the biological activity of powder products. After collecting, please store the product according to the requirements described in the datasheet. Most Adooq products are stable under the recommended conditions.
Adooq products are transported at room temperature. If you receive the product at room temperature, please rest assured, the Adooq Quality Inspection Department has conducted experiments to verify that the normal temperature placement of one month will not affect the biological activity of powder products. After collecting, please store the product according to the requirements described in the datasheet. Most Adooq products are stable under the recommended conditions.
