Product Data Sheet
PKM2 activator 3
Catalog No. A77424
PKM2 activator 3 is a potent activator of pyruvate kinase M2 (PKM2), exhibiting an AC50 value of 90 nM. This compound demonstrates favorable Caco-2 permeability, low efflux ratio, and high microsomal stability, making it an advantageous tool for in vitro studies. PKM2 activator 3 is primarily utilized in cancer research, facilitating the investigation of metabolic pathways and potential therapeutic strategies targeting PKM2.
Chemical Information
| Catalog Num | A77424 |
|---|---|
| M. Wt | 372.77 |
| Formula | C15H11ClF2N2O3S |
| Purity | >98% |
| Storage | at -20 °C 3 years (powder form); at -20 °C 6 months (Solution base) |
| CAS No. | 1346113-84-5 |
| Synonyms | |
| SMILES | FC1=C(Cl)C=C(NS(=O)(C(C=C2CC3)=C(F)C=C2NC3=O)=O)C=C1 |
Biological Activity
| Description | PKM2 activator 3 is a potent activator of pyruvate kinase M2 (PKM2), exhibiting an AC50 value of 90 nM. This compound demonstrates favorable Caco-2 permeability, low efflux ratio, and high microsomal stability, making it an advantageous tool for in vitro studies. PKM2 activator 3 is primarily utilized in cancer research, facilitating the investigation of metabolic pathways and potential therapeutic strategies targeting PKM2. |
|---|
RETURN POLICY
Adooq’s Unconditional Return Policy ensures a smooth online shopping experience for our customers. If you are in any way unsatisfied with your purchase, you may return any item(s) within 7 days of receiving it. In the event of product quality issues, either protocol related or product related problems, you may return any item(s) within 365 days from the original purchase date. Please follow the instructions below when returning products.
Adooq’s Unconditional Return Policy ensures a smooth online shopping experience for our customers. If you are in any way unsatisfied with your purchase, you may return any item(s) within 7 days of receiving it. In the event of product quality issues, either protocol related or product related problems, you may return any item(s) within 365 days from the original purchase date. Please follow the instructions below when returning products.
SHIPPING AND STORAGE
Adooq products are transported at room temperature. If you receive the product at room temperature, please rest assured, the Adooq Quality Inspection Department has conducted experiments to verify that the normal temperature placement of one month will not affect the biological activity of powder products. After collecting, please store the product according to the requirements described in the datasheet. Most Adooq products are stable under the recommended conditions.
Adooq products are transported at room temperature. If you receive the product at room temperature, please rest assured, the Adooq Quality Inspection Department has conducted experiments to verify that the normal temperature placement of one month will not affect the biological activity of powder products. After collecting, please store the product according to the requirements described in the datasheet. Most Adooq products are stable under the recommended conditions.
