Product Data Sheet

SQ 30774

Catalog No. A77519

main product photo
SQ 30774 is a selective renin inhibitor that demonstrates potent in vitro activity in primate models. This compound effectively reduces plasma renin activity (PRA) and has been shown to lower arterial blood pressure in vivo. SQ 30774 is valuable for research applications focusing on hypertension and the renin-angiotensin system, providing insights into cardiovascular regulation and potential therapeutic interventions.
Chemical Information
Catalog NumA77519
M. Wt607.74
FormulaC32H45N7O5
Purity>98%
Storageat -20 °C 3 years (powder form); at -20 °C 6 months (Solution base)
CAS No.121995-36-6
Synonyms
SMILESO=C([C@@H](N([C@H]([C@H](C1=NC=CN1)O)CC2CCCCC2)C([C@@H](NC(OC(C)(C)C)=O)CC3=CC=CC=C3)=O)CC4=CNC=N4)N
Biological Activity
DescriptionSQ 30774 is a selective renin inhibitor that demonstrates potent in vitro activity in primate models. This compound effectively reduces plasma renin activity (PRA) and has been shown to lower arterial blood pressure in vivo. SQ 30774 is valuable for research applications focusing on hypertension and the renin-angiotensin system, providing insights into cardiovascular regulation and potential therapeutic interventions.
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SHIPPING AND STORAGE
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