Product Data Sheet

U-80125

Catalog No. A77527

main product photo
U-80125 is a competitive inhibitor of human renin, demonstrating an IC50 value of 2.3 μM. This dansylated peptide is characterized by excitation and emission maxima at 340 and 530 nm, respectively. U-80125 is valuable for research focused on hypertension and cardiovascular disease, facilitating the study of renin's role in the renin-angiotensin-aldosterone system.
Chemical Information
Catalog NumA77527
M. Wt805.04
FormulaC42H60N8O6S
Purity>98%
Storageat -20 °C 3 years (powder form); at -20 °C 6 months (Solution base)
CAS No.123300-09-4
Synonyms
SMILESO=C([C@H]([C@H](CC)C)NC([C@H](C(C)C)CC([C@H](CC(C)C)NC([C@H](CC1=CN=CN1)NS(=O)(C2=CC=CC3=C(N(C)C)C=CC=C32)=O)=O)O)=O)NCC4=NC=CC=C4
Biological Activity
DescriptionU-80125 is a competitive inhibitor of human renin, demonstrating an IC50 value of 2.3 μM. This dansylated peptide is characterized by excitation and emission maxima at 340 and 530 nm, respectively. U-80125 is valuable for research focused on hypertension and cardiovascular disease, facilitating the study of renin's role in the renin-angiotensin-aldosterone system.
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