Product Data Sheet

STL1267

Catalog No. A77549

main product photo
STL1267 is a potent REV-ERB agonist, demonstrating a Ki value of 0.16 µM for REV-ERBα. This compound effectively crosses the blood-brain barrier and has been shown to inhibit the gene expression of BMAL1. STL1267 is an invaluable tool for research into circadian rhythms and metabolic processes. Its lack of cytotoxicity further enhances its suitability for in vitro studies.
Chemical Information
Catalog NumA77549
M. Wt322.75
FormulaC17H11ClN4O
Purity>98%
Storageat -20 °C 3 years (powder form); at -20 °C 6 months (Solution base)
CAS No.1429024-58-7
Synonyms
SMILESClC1=NN=C2C=CC(OC3=C(C4=CC=CC=C4)C=CC=C3)=NN12
Biological Activity
DescriptionSTL1267 is a potent REV-ERB agonist, demonstrating a Ki value of 0.16 µM for REV-ERBα. This compound effectively crosses the blood-brain barrier and has been shown to inhibit the gene expression of BMAL1. STL1267 is an invaluable tool for research into circadian rhythms and metabolic processes. Its lack of cytotoxicity further enhances its suitability for in vitro studies.
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