Product Data Sheet

RORγt inverse agonist 28

Catalog No. A77594

main product photo
RORγt inverse agonist 28 is a potent inverse agonist targeting the retinoic acid receptor-related orphan receptor gamma t (RORγt). It effectively regulates the differentiation of T helper 17 (Th17) cells and inhibits interleukin-17 (IL-17) production. This compound is valuable for research into inflammation and autoimmune diseases, providing insights into potential therapeutic approaches.
Chemical Information
Catalog NumA77594
M. Wt548.36
FormulaC23H18Cl2F3NO5S
Purity>98%
Storageat -20 °C 3 years (powder form); at -20 °C 6 months (Solution base)
CAS No.2741870-21-1
Synonyms
SMILESFC(F)(F)OC1=C(C2=C(C=C(C=C2Cl)NC([C@H](C3=CC=C(C=C3)S(C)(=O)=O)CO)=O)Cl)C=CC=C1
Biological Activity
DescriptionRORγt inverse agonist 28 is a potent inverse agonist targeting the retinoic acid receptor-related orphan receptor gamma t (RORγt). It effectively regulates the differentiation of T helper 17 (Th17) cells and inhibits interleukin-17 (IL-17) production. This compound is valuable for research into inflammation and autoimmune diseases, providing insights into potential therapeutic approaches.
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SHIPPING AND STORAGE
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