Product Data Sheet
TF-S14
Catalog No. A77600
TF-S14 is a reverse agonist of RORγt, a transcription factor critically involved in Th17 cell differentiation and cytokine production. By binding to RORγt, TF-S14 effectively inhibits the secretion of pro-inflammatory cytokines such as IL-17A, IL-21, and IL-22. This compound is valuable for research applications focused on autoimmune diseases and transplantation rejection mechanisms.
Chemical Information
| Catalog Num | A77600 |
|---|---|
| M. Wt | 397.53 |
| Formula | C22H27N3O2S |
| Purity | >98% |
| Storage | at -20 °C 3 years (powder form); at -20 °C 6 months (Solution base) |
| CAS No. | 2425563-60-4 |
| Synonyms | |
| SMILES | O=C(N1CC[C@@H](C)C[C@H]1C)C2=C(NC(C3=CN=CC=C3)=O)SC4=C2CCCC4 |
Biological Activity
| Description | TF-S14 is a reverse agonist of RORγt, a transcription factor critically involved in Th17 cell differentiation and cytokine production. By binding to RORγt, TF-S14 effectively inhibits the secretion of pro-inflammatory cytokines such as IL-17A, IL-21, and IL-22. This compound is valuable for research applications focused on autoimmune diseases and transplantation rejection mechanisms. |
|---|
RETURN POLICY
Adooq’s Unconditional Return Policy ensures a smooth online shopping experience for our customers. If you are in any way unsatisfied with your purchase, you may return any item(s) within 7 days of receiving it. In the event of product quality issues, either protocol related or product related problems, you may return any item(s) within 365 days from the original purchase date. Please follow the instructions below when returning products.
Adooq’s Unconditional Return Policy ensures a smooth online shopping experience for our customers. If you are in any way unsatisfied with your purchase, you may return any item(s) within 7 days of receiving it. In the event of product quality issues, either protocol related or product related problems, you may return any item(s) within 365 days from the original purchase date. Please follow the instructions below when returning products.
SHIPPING AND STORAGE
Adooq products are transported at room temperature. If you receive the product at room temperature, please rest assured, the Adooq Quality Inspection Department has conducted experiments to verify that the normal temperature placement of one month will not affect the biological activity of powder products. After collecting, please store the product according to the requirements described in the datasheet. Most Adooq products are stable under the recommended conditions.
Adooq products are transported at room temperature. If you receive the product at room temperature, please rest assured, the Adooq Quality Inspection Department has conducted experiments to verify that the normal temperature placement of one month will not affect the biological activity of powder products. After collecting, please store the product according to the requirements described in the datasheet. Most Adooq products are stable under the recommended conditions.
