Product Data Sheet
CD12681
Catalog No. A77606
CD12681 is a selective inverse agonist of RORγ, exhibiting IC50 values of 19 nM and 10 nM against RORγ GAL4 and CD4-IL-17 cells, respectively. This compound effectively reduces IL-17-mediated inflammatory cell recruitment, making it a valuable tool for studying inflammatory pathways. CD12681 shows promise for research applications in conditions such as psoriasis, facilitating the exploration of novel therapeutic strategies.
Chemical Information
| Catalog Num | A77606 |
|---|---|
| M. Wt | 471.61 |
| Formula | C25H33N3O4S |
| Purity | >98% |
| Storage | at -20 °C 3 years (powder form); at -20 °C 6 months (Solution base) |
| CAS No. | 1952239-59-6 |
| Synonyms | |
| SMILES | O=S(C1=CC(NC(N2CC3CCOCC3)=O)=C2C=C1)(N(C4=CC=C(C)C=C4C)CC(C)C)=O |
Biological Activity
| Description | CD12681 is a selective inverse agonist of RORγ, exhibiting IC50 values of 19 nM and 10 nM against RORγ GAL4 and CD4-IL-17 cells, respectively. This compound effectively reduces IL-17-mediated inflammatory cell recruitment, making it a valuable tool for studying inflammatory pathways. CD12681 shows promise for research applications in conditions such as psoriasis, facilitating the exploration of novel therapeutic strategies. |
|---|
RETURN POLICY
Adooq’s Unconditional Return Policy ensures a smooth online shopping experience for our customers. If you are in any way unsatisfied with your purchase, you may return any item(s) within 7 days of receiving it. In the event of product quality issues, either protocol related or product related problems, you may return any item(s) within 365 days from the original purchase date. Please follow the instructions below when returning products.
Adooq’s Unconditional Return Policy ensures a smooth online shopping experience for our customers. If you are in any way unsatisfied with your purchase, you may return any item(s) within 7 days of receiving it. In the event of product quality issues, either protocol related or product related problems, you may return any item(s) within 365 days from the original purchase date. Please follow the instructions below when returning products.
SHIPPING AND STORAGE
Adooq products are transported at room temperature. If you receive the product at room temperature, please rest assured, the Adooq Quality Inspection Department has conducted experiments to verify that the normal temperature placement of one month will not affect the biological activity of powder products. After collecting, please store the product according to the requirements described in the datasheet. Most Adooq products are stable under the recommended conditions.
Adooq products are transported at room temperature. If you receive the product at room temperature, please rest assured, the Adooq Quality Inspection Department has conducted experiments to verify that the normal temperature placement of one month will not affect the biological activity of powder products. After collecting, please store the product according to the requirements described in the datasheet. Most Adooq products are stable under the recommended conditions.
