Product Data Sheet

Cintirorgon sodium

Catalog No. A77614

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Cintirorgon sodium is a selective and orally bioavailable RORγ agonist that modulates gene expression in RORγ-expressing T lymphocytes. This compound enhances effector functions and reduces immunosuppressive mechanisms, contributing to decreased tumor growth and improved survival rates in various preclinical models. Cintirorgon sodium is a valuable tool for research applications focused on immunotherapy and cancer biology.
Chemical Information
Catalog NumA77614
M. Wt625.51
FormulaC27H22F6NNaO6S
Purity>98%
Storageat -20 °C 3 years (powder form); at -20 °C 6 months (Solution base)
CAS No.2055538-47-9
SynonymsLYC-55716 sodium
SMILESO=C(O[Na])C(C)(C)C[C@@H]1OC2=CC=C(C3=CC(F)=CC(OC(F)F)=C3)C=C2N(S(=O)(C4=CC=CC(C(F)(F)F)=C4)=O)C1
Biological Activity
DescriptionCintirorgon sodium is a selective and orally bioavailable RORγ agonist that modulates gene expression in RORγ-expressing T lymphocytes. This compound enhances effector functions and reduces immunosuppressive mechanisms, contributing to decreased tumor growth and improved survival rates in various preclinical models. Cintirorgon sodium is a valuable tool for research applications focused on immunotherapy and cancer biology.
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SHIPPING AND STORAGE
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