Product Data Sheet

WNK1-IN-1

Catalog No. A77645

main product photo
WNK1-IN-1 is a selective inhibitor of WNK1, exhibiting an IC50 of 1.6 μM. It effectively inhibits the phosphorylation of OSR1 with an IC50 of 4.3 μM. This compound is relevant for studies focused on blood pressure regulation and various aspects of cancer research, making it a valuable tool for elucidating the role of WNK1 in pathophysiological processes.
Chemical Information
Catalog NumA77645
M. Wt446.14
FormulaC13H15BrCl2N2O4S
Purity>98%
Storageat -20 °C 3 years (powder form); at -20 °C 6 months (Solution base)
CAS No.324022-39-1
Synonyms
SMILESO=[N+](C1=CC(S(=O)(C(Cl)(Br)Cl)=O)=CC=C1NC2CCCCC2)[O-]
Biological Activity
DescriptionWNK1-IN-1 is a selective inhibitor of WNK1, exhibiting an IC50 of 1.6 μM. It effectively inhibits the phosphorylation of OSR1 with an IC50 of 4.3 μM. This compound is relevant for studies focused on blood pressure regulation and various aspects of cancer research, making it a valuable tool for elucidating the role of WNK1 in pathophysiological processes.
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