Product Data Sheet
CRA-2059
Catalog No. A77688
CRA-2059 is a highly selective tryptase inhibitor with a Ki of 620 pM for recombinant human tryptase-β (rHTβ). This compound demonstrates potent inhibition of tryptase activity, making it a valuable tool for research focused on allergic responses and tissue remodeling. Its specificity for tryptase positions CRA-2059 as an important reagent in studies of inflammatory diseases and related therapeutic development.
Chemical Information
| Catalog Num | A77688 |
|---|---|
| M. Wt | 750.80 |
| Formula | C34H46N12O8 |
| Purity | >98% |
| Storage | at -20 °C 3 years (powder form); at -20 °C 6 months (Solution base) |
| CAS No. | 256649-36-2 |
| Synonyms | |
| SMILES | NC(NC1=CC=C(CNC(N2CCN(C(O[C@@H]3COC4[C@H](OC(N5CCN(C(NCC6=CC=C(NC(N)=N)C=C6)=O)CC5)=O)COC34)=O)CC2)=O)C=C1)=N |
Biological Activity
| Description | CRA-2059 is a highly selective tryptase inhibitor with a Ki of 620 pM for recombinant human tryptase-β (rHTβ). This compound demonstrates potent inhibition of tryptase activity, making it a valuable tool for research focused on allergic responses and tissue remodeling. Its specificity for tryptase positions CRA-2059 as an important reagent in studies of inflammatory diseases and related therapeutic development. |
|---|
RETURN POLICY
Adooq’s Unconditional Return Policy ensures a smooth online shopping experience for our customers. If you are in any way unsatisfied with your purchase, you may return any item(s) within 7 days of receiving it. In the event of product quality issues, either protocol related or product related problems, you may return any item(s) within 365 days from the original purchase date. Please follow the instructions below when returning products.
Adooq’s Unconditional Return Policy ensures a smooth online shopping experience for our customers. If you are in any way unsatisfied with your purchase, you may return any item(s) within 7 days of receiving it. In the event of product quality issues, either protocol related or product related problems, you may return any item(s) within 365 days from the original purchase date. Please follow the instructions below when returning products.
SHIPPING AND STORAGE
Adooq products are transported at room temperature. If you receive the product at room temperature, please rest assured, the Adooq Quality Inspection Department has conducted experiments to verify that the normal temperature placement of one month will not affect the biological activity of powder products. After collecting, please store the product according to the requirements described in the datasheet. Most Adooq products are stable under the recommended conditions.
Adooq products are transported at room temperature. If you receive the product at room temperature, please rest assured, the Adooq Quality Inspection Department has conducted experiments to verify that the normal temperature placement of one month will not affect the biological activity of powder products. After collecting, please store the product according to the requirements described in the datasheet. Most Adooq products are stable under the recommended conditions.
