Product Data Sheet

CatB-IN-1

Catalog No. A77698

main product photo
CatB-IN-1 is a potent inhibitor of serine/threonine proteases, specifically targeting cathepsin B. This compound exhibits significant anti-invasive activity in various cellular models, effectively reducing the invasiveness of tumor cells such as MCF-10A neoT. Research indicates that CatB-IN-1 can modulate intracellular protein metabolism, thereby influencing tumor cell behavior. Its structure-activity relationship highlights its capability to engage multiple functions of cathepsin B, making it a valuable tool for studies on tumor invasion and metastasis.
Chemical Information
Catalog NumA77698
M. Wt258.23
FormulaC12H10N4O3
Purity>98%
Storageat -20 °C 3 years (powder form); at -20 °C 6 months (Solution base)
CAS No.1417737-67-7
Synonyms
SMILESN#CCNCC1=CC([N+]([O-])=O)=C2C=CC=NC2=C1O
Biological Activity
DescriptionCatB-IN-1 is a potent inhibitor of serine/threonine proteases, specifically targeting cathepsin B. This compound exhibits significant anti-invasive activity in various cellular models, effectively reducing the invasiveness of tumor cells such as MCF-10A neoT. Research indicates that CatB-IN-1 can modulate intracellular protein metabolism, thereby influencing tumor cell behavior. Its structure-activity relationship highlights its capability to engage multiple functions of cathepsin B, making it a valuable tool for studies on tumor invasion and metastasis.
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