Product Data Sheet

MOL-6131

Catalog No. A77727

main product photo
MOL-6131 is a highly selective, reversible inhibitor of tryptase, exhibiting a Ki value of 45 nM. This compound effectively reduces key features of allergic airway inflammation, including eosinophil infiltration in lung tissue, goblet cell hyperplasia, and mucus occlusion of airways. It serves as a valuable tool for research focused on respiratory diseases and allergic responses.
Chemical Information
Catalog NumA77727
M. Wt756.89
FormulaC43H48N8O5
Purity>98%
Storageat -20 °C 3 years (powder form); at -20 °C 6 months (Solution base)
CAS No.583868-50-2
Synonyms
SMILESO=C(CC1=CC=C(C=C1)N)NCCCC(N2CCC(C3C=CC(N4C(N(CC5=CC=CC6=C5C=CC=C6)C(N43)=O)=O)C(NCC7=CC=C(CN)C=C7)=O)CC2)=O
Biological Activity
DescriptionMOL-6131 is a highly selective, reversible inhibitor of tryptase, exhibiting a Ki value of 45 nM. This compound effectively reduces key features of allergic airway inflammation, including eosinophil infiltration in lung tissue, goblet cell hyperplasia, and mucus occlusion of airways. It serves as a valuable tool for research focused on respiratory diseases and allergic responses.
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