Product Data Sheet

Manusiran

Catalog No. A77765

main product photo
Manusiran (SLN124) is a GalNAc-conjugated 19-mer siRNA targeting TMPRSS6 (transmembrane protease serine 6). It effectively reduces plasma iron levels while increasing hepcidin expression in healthy individuals. This compound is primarily used in research applications focused on iron metabolism and disorders related to iron homeostasis.
Chemical Information
Catalog NumA77765
M. Wt14058.53
FormulaC434H570F19N145O270P40S10
Purity>98%
Storageat -20 °C 3 years (powder form); at -20 °C 6 months (Solution base)
CAS No.2646704-10-9
SynonymsDivesiran
SMILES[Manusiran]
Biological Activity
DescriptionManusiran (SLN124) is a GalNAc-conjugated 19-mer siRNA targeting TMPRSS6 (transmembrane protease serine 6). It effectively reduces plasma iron levels while increasing hepcidin expression in healthy individuals. This compound is primarily used in research applications focused on iron metabolism and disorders related to iron homeostasis.
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