Product Data Sheet

SI-113

Catalog No. A77829

main product photo
SI-113 is an inhibitor of SGK1, demonstrating an IC50 of 600 nM. This compound is known to induce autophagy, making it a valuable tool for studying cellular mechanisms related to SGK1 activity. It has potential applications in research areas such as cancer biology and neurodegenerative diseases, where modulation of autophagy may be beneficial.
Chemical Information
Catalog NumA77829
M. Wt400.48
FormulaC23H24N6O
Purity>98%
Storageat -20 °C 3 years (powder form); at -20 °C 6 months (Solution base)
CAS No.1392816-46-4
Synonyms
SMILESOCCNC1=NC(NCCC2=CC=CC=C2)=C3C(N(/C=C/C4=CC=CC=C4)N=C3)=N1
Biological Activity
DescriptionSI-113 is an inhibitor of SGK1, demonstrating an IC50 of 600 nM. This compound is known to induce autophagy, making it a valuable tool for studying cellular mechanisms related to SGK1 activity. It has potential applications in research areas such as cancer biology and neurodegenerative diseases, where modulation of autophagy may be beneficial.
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