Product Data Sheet

Steroid sulfatase-IN-3

Catalog No. A77874

main product photo
Steroid sulfatase-IN-3 is a potent inhibitor of steroid sulfatase (STS) with an IC50 value of 25.8 nM. This compound exhibits significant antiproliferative activity against T-47D estrogen-dependent breast cancer cells, demonstrating an IC50 of 1.04 µM. Steroid sulfatase-IN-3 is primarily utilized in cancer research to explore the role of STS in hormone-dependent tumor progression and treatment resistance.
Chemical Information
Catalog NumA77874
M. Wt384.88
FormulaC17H21ClN2O4S
Purity>98%
Storageat -20 °C 3 years (powder form); at -20 °C 6 months (Solution base)
CAS No.2413880-53-0
Synonyms
SMILESO=S(OC1=CC=C(C(NC2(C3)CC4CC3CC(C4)C2)=O)C=C1Cl)(N)=O
Biological Activity
DescriptionSteroid sulfatase-IN-3 is a potent inhibitor of steroid sulfatase (STS) with an IC50 value of 25.8 nM. This compound exhibits significant antiproliferative activity against T-47D estrogen-dependent breast cancer cells, demonstrating an IC50 of 1.04 µM. Steroid sulfatase-IN-3 is primarily utilized in cancer research to explore the role of STS in hormone-dependent tumor progression and treatment resistance.
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