Product Data Sheet
Dabigatran-d4 hydrochloride
Catalog No. A77891
Dabigatran-d4 hydrochloride is a deuterium-labeled analogue of Dabigatran, a selective direct thrombin inhibitor (DTI) that exhibits a Ki value of 4.5 nM. This compound is utilized in research applications focused on anticoagulant therapies and thrombin inhibition mechanisms, providing a stable isotope label for pharmacokinetic studies and drug metabolism investigations. Its use in experimental settings supports the elucidation of drug interactions and blood coagulation pathways.
Chemical Information
| Catalog Num | A77891 |
|---|---|
| M. Wt | 512.00 |
| Formula | C25H22D4ClN7O3 |
| Purity | >98% |
| Storage | at -20 °C 3 years (powder form); at -20 °C 6 months (Solution base) |
| CAS No. | 2070015-06-2 |
| Synonyms | BIBR-953-d4 hydrochloride |
| SMILES | N=C(N)C(C([2H])=C1[2H])=C([2H])C([2H])=C1NCC2=NC(C=C3C(N(CCC(O)=O)C4=NC=CC=C4)=O)=C(C=C3)N2C.Cl |
Biological Activity
| Description | Dabigatran-d4 hydrochloride is a deuterium-labeled analogue of Dabigatran, a selective direct thrombin inhibitor (DTI) that exhibits a Ki value of 4.5 nM. This compound is utilized in research applications focused on anticoagulant therapies and thrombin inhibition mechanisms, providing a stable isotope label for pharmacokinetic studies and drug metabolism investigations. Its use in experimental settings supports the elucidation of drug interactions and blood coagulation pathways. |
|---|
RETURN POLICY
Adooq’s Unconditional Return Policy ensures a smooth online shopping experience for our customers. If you are in any way unsatisfied with your purchase, you may return any item(s) within 7 days of receiving it. In the event of product quality issues, either protocol related or product related problems, you may return any item(s) within 365 days from the original purchase date. Please follow the instructions below when returning products.
Adooq’s Unconditional Return Policy ensures a smooth online shopping experience for our customers. If you are in any way unsatisfied with your purchase, you may return any item(s) within 7 days of receiving it. In the event of product quality issues, either protocol related or product related problems, you may return any item(s) within 365 days from the original purchase date. Please follow the instructions below when returning products.
SHIPPING AND STORAGE
Adooq products are transported at room temperature. If you receive the product at room temperature, please rest assured, the Adooq Quality Inspection Department has conducted experiments to verify that the normal temperature placement of one month will not affect the biological activity of powder products. After collecting, please store the product according to the requirements described in the datasheet. Most Adooq products are stable under the recommended conditions.
Adooq products are transported at room temperature. If you receive the product at room temperature, please rest assured, the Adooq Quality Inspection Department has conducted experiments to verify that the normal temperature placement of one month will not affect the biological activity of powder products. After collecting, please store the product according to the requirements described in the datasheet. Most Adooq products are stable under the recommended conditions.
