Product Data Sheet
Dabigatran-d4
Catalog No. A77892
Dabigatran-d4 is a deuterated form of Dabigatran, a potent and reversible direct thrombin inhibitor with a Ki of 4.5 nM. This oral anticoagulant is effective in preventing thrombin-induced platelet aggregation, exhibiting an IC50 value of 10 nM. Dabigatran-d4 can be utilized in pharmacokinetic studies and metabolic research, providing a valuable tool for understanding thrombin inhibition in various biological contexts.
Chemical Information
| Catalog Num | A77892 |
|---|---|
| M. Wt | 475.54 |
| Formula | C25H21D4N7O3 |
| Purity | >98% |
| Storage | at -20 °C 3 years (powder form); at -20 °C 6 months (Solution base) |
| CAS No. | 1618637-32-3 |
| Synonyms | BIBR 953-d4; BIBR 953ZW-d4 |
| SMILES | N=C(N)C(C([2H])=C1[2H])=C([2H])C([2H])=C1NCC2=NC(C=C3C(N(CCC(O)=O)C4=NC=CC=C4)=O)=C(C=C3)N2C |
Biological Activity
| Description | Dabigatran-d4 is a deuterated form of Dabigatran, a potent and reversible direct thrombin inhibitor with a Ki of 4.5 nM. This oral anticoagulant is effective in preventing thrombin-induced platelet aggregation, exhibiting an IC50 value of 10 nM. Dabigatran-d4 can be utilized in pharmacokinetic studies and metabolic research, providing a valuable tool for understanding thrombin inhibition in various biological contexts. |
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RETURN POLICY
Adooq’s Unconditional Return Policy ensures a smooth online shopping experience for our customers. If you are in any way unsatisfied with your purchase, you may return any item(s) within 7 days of receiving it. In the event of product quality issues, either protocol related or product related problems, you may return any item(s) within 365 days from the original purchase date. Please follow the instructions below when returning products.
Adooq’s Unconditional Return Policy ensures a smooth online shopping experience for our customers. If you are in any way unsatisfied with your purchase, you may return any item(s) within 7 days of receiving it. In the event of product quality issues, either protocol related or product related problems, you may return any item(s) within 365 days from the original purchase date. Please follow the instructions below when returning products.
SHIPPING AND STORAGE
Adooq products are transported at room temperature. If you receive the product at room temperature, please rest assured, the Adooq Quality Inspection Department has conducted experiments to verify that the normal temperature placement of one month will not affect the biological activity of powder products. After collecting, please store the product according to the requirements described in the datasheet. Most Adooq products are stable under the recommended conditions.
Adooq products are transported at room temperature. If you receive the product at room temperature, please rest assured, the Adooq Quality Inspection Department has conducted experiments to verify that the normal temperature placement of one month will not affect the biological activity of powder products. After collecting, please store the product according to the requirements described in the datasheet. Most Adooq products are stable under the recommended conditions.
