Product Data Sheet

S-18326

Catalog No. A77923

main product photo
S-18326 is an orally active direct thrombin inhibitor that functions by reversibly binding to the active site of thrombin, thereby preventing the conversion of fibrinogen to fibrin and inhibiting thrombus formation. This compound effectively prolongs clotting times in human plasma and has shown antithrombotic efficacy in various animal models while maintaining normal platelet levels. S-18326 is suitable for research applications related to thromboembolic diseases.
Chemical Information
Catalog NumA77923
M. Wt488.39
FormulaC23H37BN6O5
Purity>98%
Storageat -20 °C 3 years (powder form); at -20 °C 6 months (Solution base)
CAS No.167843-21-2
Synonyms
SMILESO=C(N(C1CCCC1)CC(N[C@@H](CCCNC(N)=N)B(O)O)=O)[C@H](NC(C)=O)CC2=CC=CC=C2
Biological Activity
DescriptionS-18326 is an orally active direct thrombin inhibitor that functions by reversibly binding to the active site of thrombin, thereby preventing the conversion of fibrinogen to fibrin and inhibiting thrombus formation. This compound effectively prolongs clotting times in human plasma and has shown antithrombotic efficacy in various animal models while maintaining normal platelet levels. S-18326 is suitable for research applications related to thromboembolic diseases.
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