Product Data Sheet

BMS 180742

Catalog No. A77935

main product photo
BMS 180742 is a selective thrombin exosite inhibitor that disrupts thrombin's ability to interact with its substrates. It exhibits significant inhibition of thrombin-mediated processes, making it a valuable tool for investigating coagulation pathways. This compound is particularly useful in research applications focusing on the modulation of hemostasis and thrombin-related disorders. Notably, BMS 180742 does not exhibit inhibition of arterial thrombosis, providing insights into selective targeting in thrombosis research.
Chemical Information
Catalog NumA77935
M. Wt1404.52
FormulaC67H93N11O22
Purity>98%
Storageat -20 °C 3 years (powder form); at -20 °C 6 months (Solution base)
CAS No.138828-04-3
Synonyms
SMILESC([C@@H](NC(=O)[C@H]1N(C([C@@H](NC([C@H](CC2=CC=CC=C2)NC(CCC(O)=O)=O)=O)CCC(O)=O)=O)CCC1)[C@H](CC)C)(=O)N3[C@H](C(N[C@H](C(N[C@H](C(N[C@@H](CC4=CC=C(O)C=C4)C(N[C@@H](CC5CCCCC5)C(N[C@@H](CCC(N)=O)C(O)=O)=O)=O)=O)CCC(O)=O)=O)CCC(O)=O)=O)CCC3
Biological Activity
DescriptionBMS 180742 is a selective thrombin exosite inhibitor that disrupts thrombin's ability to interact with its substrates. It exhibits significant inhibition of thrombin-mediated processes, making it a valuable tool for investigating coagulation pathways. This compound is particularly useful in research applications focusing on the modulation of hemostasis and thrombin-related disorders. Notably, BMS 180742 does not exhibit inhibition of arterial thrombosis, providing insights into selective targeting in thrombosis research.
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