BMS 180742
Catalog No. A77935

BMS 180742 is a selective thrombin exosite inhibitor that disrupts thrombin's ability to interact with its substrates. It exhibits significant inhibition of thrombin-mediated processes, making it a valuable tool for investigating coagulation pathways. This compound is particularly useful in research applications focusing on the modulation of hemostasis and thrombin-related disorders. Notably, BMS 180742 does not exhibit inhibition of arterial thrombosis, providing insights into selective targeting in thrombosis research.
Chemical Information
| Catalog Num | A77935 |
|---|---|
| M. Wt | 1404.52 |
| Formula | C67H93N11O22 |
| Purity | >98% |
| Storage | at -20 °C 3 years (powder form); at -20 °C 6 months (Solution base) |
| CAS No. | 138828-04-3 |
| Synonyms | |
| SMILES | C([C@@H](NC(=O)[C@H]1N(C([C@@H](NC([C@H](CC2=CC=CC=C2)NC(CCC(O)=O)=O)=O)CCC(O)=O)=O)CCC1)[C@H](CC)C)(=O)N3[C@H](C(N[C@H](C(N[C@H](C(N[C@@H](CC4=CC=C(O)C=C4)C(N[C@@H](CC5CCCCC5)C(N[C@@H](CCC(N)=O)C(O)=O)=O)=O)=O)CCC(O)=O)=O)CCC(O)=O)=O)CCC3 |
Biological Activity
| Description | BMS 180742 is a selective thrombin exosite inhibitor that disrupts thrombin's ability to interact with its substrates. It exhibits significant inhibition of thrombin-mediated processes, making it a valuable tool for investigating coagulation pathways. This compound is particularly useful in research applications focusing on the modulation of hemostasis and thrombin-related disorders. Notably, BMS 180742 does not exhibit inhibition of arterial thrombosis, providing insights into selective targeting in thrombosis research. |
|---|
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Adooq’s Unconditional Return Policy ensures a smooth online shopping experience for our customers. If you are in any way unsatisfied with your purchase, you may return any item(s) within 7 days of receiving it. In the event of product quality issues, either protocol related or product related problems, you may return any item(s) within 365 days from the original purchase date. Please follow the instructions below when returning products.
SHIPPING AND STORAGE
Adooq products are transported at room temperature. If you receive the product at room temperature, please rest assured, the Adooq Quality Inspection Department has conducted experiments to verify that the normal temperature placement of one month will not affect the biological activity of powder products. After collecting, please store the product according to the requirements described in the datasheet. Most Adooq products are stable under the recommended conditions.
Adooq products are transported at room temperature. If you receive the product at room temperature, please rest assured, the Adooq Quality Inspection Department has conducted experiments to verify that the normal temperature placement of one month will not affect the biological activity of powder products. After collecting, please store the product according to the requirements described in the datasheet. Most Adooq products are stable under the recommended conditions.


