Product Data Sheet

Ro 09-1679

Catalog No. A77949

main product photo
Ro 09-1679 is a potent thrombin inhibitor with an IC50 of 33.6 μM, demonstrating significant inhibition of thrombin activity. Additionally, it effectively inhibits factor Xa, trypsin, and papain, with IC50 values of 3.3 μM, 0.04 μM, and 0.0346 μM, respectively. This compound is valuable for research applications focused on coagulation pathways, providing insights into thrombin's role in hemostasis and potential therapeutic interventions.
Chemical Information
Catalog NumA77949
M. Wt525.60
FormulaC22H39N9O6
Purity>98%
Storageat -20 °C 3 years (powder form); at -20 °C 6 months (Solution base)
CAS No.141426-89-3
Synonyms
SMILESNC(NCCC[C@@H](C(N[C@@H](CC(C)C)C(N[C@H](C=O)CCCNC(N)=N)=O)=O)NC(/C=C/C(O)=O)=O)=N
Biological Activity
DescriptionRo 09-1679 is a potent thrombin inhibitor with an IC50 of 33.6 μM, demonstrating significant inhibition of thrombin activity. Additionally, it effectively inhibits factor Xa, trypsin, and papain, with IC50 values of 3.3 μM, 0.04 μM, and 0.0346 μM, respectively. This compound is valuable for research applications focused on coagulation pathways, providing insights into thrombin's role in hemostasis and potential therapeutic interventions.
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