Product Data Sheet

LY 806303

Catalog No. A77960

main product photo
LY 806303 is a selective inhibitor of human α-thrombin, functioning primarily through the acylation of Ser-205 within the enzyme's catalytic triad. This modification disrupts the enzymatic activity of thrombin, delineating its role in various coagulation processes. LY 806303 is valuable for research applications focused on thrombin's involvement in hemostasis and thrombosis, providing insights into therapeutic strategies for related diseases.
Chemical Information
Catalog NumA77960
M. Wt318.34
FormulaC16H14O5S
Purity>98%
Storageat -20 °C 3 years (powder form); at -20 °C 6 months (Solution base)
CAS No.149725-15-5
Synonyms
SMILESO=C(OC)C1=C(C2=C(O1)C3=CC=CC=C3S2)OC(C(C)C)=O
Biological Activity
DescriptionLY 806303 is a selective inhibitor of human α-thrombin, functioning primarily through the acylation of Ser-205 within the enzyme's catalytic triad. This modification disrupts the enzymatic activity of thrombin, delineating its role in various coagulation processes. LY 806303 is valuable for research applications focused on thrombin's involvement in hemostasis and thrombosis, providing insights into therapeutic strategies for related diseases.
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