Product Data Sheet

RWJ-671818

Catalog No. A77961

main product photo
RWJ-671818 is a potent oral inhibitor of human α-thrombin, exhibiting a Ki of 1.3 nM. This compound is particularly relevant in the study of venous and arterial thrombosis, providing insights into thrombotic mechanisms and potential therapeutic interventions. Its specificity for α-thrombin makes it a valuable tool in anticoagulant research.
Chemical Information
Catalog NumA77961
M. Wt423.42
FormulaC18H23F2N7O3
Purity>98%
Storageat -20 °C 3 years (powder form); at -20 °C 6 months (Solution base)
CAS No.252271-49-1
Synonyms
SMILESO=C(CN1C(C(NCC(F)(C2=CC=CC=C2)F)=NC=C1C)=O)NCCONC(N)=N
Biological Activity
DescriptionRWJ-671818 is a potent oral inhibitor of human α-thrombin, exhibiting a Ki of 1.3 nM. This compound is particularly relevant in the study of venous and arterial thrombosis, providing insights into thrombotic mechanisms and potential therapeutic interventions. Its specificity for α-thrombin makes it a valuable tool in anticoagulant research.
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