Product Data Sheet
Atecegatran
Catalog No. A77969
Atecegatran is an orally active competitive thrombin inhibitor targeting thrombin with a Ki value of 2-4 nM. By blocking thrombin's interaction with fibrin and thrombomodulin, it effectively inhibits platelet activation and aggregation. Demonstrating significant anticoagulant properties, Atecegatran exhibits an IC50 range of 93 to 220 nM in various plasma coagulation assays. This reagent is valuable for research focused on thromboembolic disorders and related cardiovascular studies.
Chemical Information
| Catalog Num | A77969 |
|---|---|
| M. Wt | 466.87 |
| Formula | C21H21ClF2N4O4 |
| Purity | >98% |
| Storage | at -20 °C 3 years (powder form); at -20 °C 6 months (Solution base) |
| CAS No. | 433937-74-7 |
| Synonyms | AR-H067637 |
| SMILES | O=C([C@H](O)C1=CC(OC(F)F)=CC(Cl)=C1)N(CC2)[C@@H]2C(NCC3=CC=C(C=C3)C(N)=N)=O |
Biological Activity
| Description | Atecegatran is an orally active competitive thrombin inhibitor targeting thrombin with a Ki value of 2-4 nM. By blocking thrombin's interaction with fibrin and thrombomodulin, it effectively inhibits platelet activation and aggregation. Demonstrating significant anticoagulant properties, Atecegatran exhibits an IC50 range of 93 to 220 nM in various plasma coagulation assays. This reagent is valuable for research focused on thromboembolic disorders and related cardiovascular studies. |
|---|
RETURN POLICY
Adooq’s Unconditional Return Policy ensures a smooth online shopping experience for our customers. If you are in any way unsatisfied with your purchase, you may return any item(s) within 7 days of receiving it. In the event of product quality issues, either protocol related or product related problems, you may return any item(s) within 365 days from the original purchase date. Please follow the instructions below when returning products.
Adooq’s Unconditional Return Policy ensures a smooth online shopping experience for our customers. If you are in any way unsatisfied with your purchase, you may return any item(s) within 7 days of receiving it. In the event of product quality issues, either protocol related or product related problems, you may return any item(s) within 365 days from the original purchase date. Please follow the instructions below when returning products.
SHIPPING AND STORAGE
Adooq products are transported at room temperature. If you receive the product at room temperature, please rest assured, the Adooq Quality Inspection Department has conducted experiments to verify that the normal temperature placement of one month will not affect the biological activity of powder products. After collecting, please store the product according to the requirements described in the datasheet. Most Adooq products are stable under the recommended conditions.
Adooq products are transported at room temperature. If you receive the product at room temperature, please rest assured, the Adooq Quality Inspection Department has conducted experiments to verify that the normal temperature placement of one month will not affect the biological activity of powder products. After collecting, please store the product according to the requirements described in the datasheet. Most Adooq products are stable under the recommended conditions.
