Product Data Sheet
ent-11α-Hydroxy-15-oxokaur-16-en-19-oic acid
Catalog No. A78087
ent-11α-Hydroxy-15-oxokaur-16-en-19-oic acid is a potent tyrosinase inhibitor that effectively reduces melanin synthesis. Isolated from Pteris fern, this compound targets the melanogenesis transcription factor microphthalmia-associated transcription factor (MITF), modulating melanin production. Key structural features including the 11α-OH, 15-oxo, and 16-en functionalities contribute to its inhibitory effects on melanin synthesis, while the 19-COOH moiety may help mitigate cytotoxicity associated with related compounds. This reagent is valuable in research focused on skin pigmentation and potential therapeutic applications for hyperpigmentation disorders.
Chemical Information
| Catalog Num | A78087 |
|---|---|
| M. Wt | 332.43 |
| Formula | C20H28O4 |
| Purity | >98% |
| Storage | at -20 °C 3 years (powder form); at -20 °C 6 months (Solution base) |
| CAS No. | 57719-81-0 |
| Synonyms | |
| SMILES | O=C1C([C@@]2([H])C[C@]13[C@]([C@@H](O)C2)([H])[C@]4([C@]([C@@](C)(CCC4)C(O)=O)([H])CC3)C)=C |
Biological Activity
| Description | ent-11α-Hydroxy-15-oxokaur-16-en-19-oic acid is a potent tyrosinase inhibitor that effectively reduces melanin synthesis. Isolated from Pteris fern, this compound targets the melanogenesis transcription factor microphthalmia-associated transcription factor (MITF), modulating melanin production. Key structural features including the 11α-OH, 15-oxo, and 16-en functionalities contribute to its inhibitory effects on melanin synthesis, while the 19-COOH moiety may help mitigate cytotoxicity associated with related compounds. This reagent is valuable in research focused on skin pigmentation and potential therapeutic applications for hyperpigmentation disorders. |
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RETURN POLICY
Adooq’s Unconditional Return Policy ensures a smooth online shopping experience for our customers. If you are in any way unsatisfied with your purchase, you may return any item(s) within 7 days of receiving it. In the event of product quality issues, either protocol related or product related problems, you may return any item(s) within 365 days from the original purchase date. Please follow the instructions below when returning products.
Adooq’s Unconditional Return Policy ensures a smooth online shopping experience for our customers. If you are in any way unsatisfied with your purchase, you may return any item(s) within 7 days of receiving it. In the event of product quality issues, either protocol related or product related problems, you may return any item(s) within 365 days from the original purchase date. Please follow the instructions below when returning products.
SHIPPING AND STORAGE
Adooq products are transported at room temperature. If you receive the product at room temperature, please rest assured, the Adooq Quality Inspection Department has conducted experiments to verify that the normal temperature placement of one month will not affect the biological activity of powder products. After collecting, please store the product according to the requirements described in the datasheet. Most Adooq products are stable under the recommended conditions.
Adooq products are transported at room temperature. If you receive the product at room temperature, please rest assured, the Adooq Quality Inspection Department has conducted experiments to verify that the normal temperature placement of one month will not affect the biological activity of powder products. After collecting, please store the product according to the requirements described in the datasheet. Most Adooq products are stable under the recommended conditions.
