Product Data Sheet
Aspochalasin I
Catalog No. A78091
Aspochalasin I is a potent tyrosinase inhibitor that effectively suppresses melanogenesis, achieving an IC50 of 22.4 μM. This compound also demonstrates cytotoxic effects against various cancer cell lines, including NCI-H460, MCF-7, and SF-268, with IC50 values of 22.1, 33.4, and 19.9 μM, respectively. Due to its role in inhibiting melanin production, Aspochalasin I can be utilized in research aimed at developing skin whitening agents and exploring therapeutic avenues in cancer treatment.
Chemical Information
| Catalog Num | A78091 |
|---|---|
| M. Wt | 417.54 |
| Formula | C24H35NO5 |
| Purity | >98% |
| Storage | at -20 °C 3 years (powder form); at -20 °C 6 months (Solution base) |
| CAS No. | 670225-69-1 |
| Synonyms | |
| SMILES | CC1=C[C@@](/C=C(C)/CC[C@H](O)[C@H](O)/C=C/2)([H])[C@@]3(OC2=O)[C@@]([C@H](CC(C)C)NC3=O)([H])[C@@H]1C |
Biological Activity
| Description | Aspochalasin I is a potent tyrosinase inhibitor that effectively suppresses melanogenesis, achieving an IC50 of 22.4 μM. This compound also demonstrates cytotoxic effects against various cancer cell lines, including NCI-H460, MCF-7, and SF-268, with IC50 values of 22.1, 33.4, and 19.9 μM, respectively. Due to its role in inhibiting melanin production, Aspochalasin I can be utilized in research aimed at developing skin whitening agents and exploring therapeutic avenues in cancer treatment. |
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RETURN POLICY
Adooq’s Unconditional Return Policy ensures a smooth online shopping experience for our customers. If you are in any way unsatisfied with your purchase, you may return any item(s) within 7 days of receiving it. In the event of product quality issues, either protocol related or product related problems, you may return any item(s) within 365 days from the original purchase date. Please follow the instructions below when returning products.
Adooq’s Unconditional Return Policy ensures a smooth online shopping experience for our customers. If you are in any way unsatisfied with your purchase, you may return any item(s) within 7 days of receiving it. In the event of product quality issues, either protocol related or product related problems, you may return any item(s) within 365 days from the original purchase date. Please follow the instructions below when returning products.
SHIPPING AND STORAGE
Adooq products are transported at room temperature. If you receive the product at room temperature, please rest assured, the Adooq Quality Inspection Department has conducted experiments to verify that the normal temperature placement of one month will not affect the biological activity of powder products. After collecting, please store the product according to the requirements described in the datasheet. Most Adooq products are stable under the recommended conditions.
Adooq products are transported at room temperature. If you receive the product at room temperature, please rest assured, the Adooq Quality Inspection Department has conducted experiments to verify that the normal temperature placement of one month will not affect the biological activity of powder products. After collecting, please store the product according to the requirements described in the datasheet. Most Adooq products are stable under the recommended conditions.
