Product Data Sheet
Taraxinic acid
Catalog No. A78102
Taraxinic acid is a potent inhibitor of tyrosinase, an enzyme crucial for melanin biosynthesis. Derived from the roots of Taraxacum flavostylum and Taraxacum lucidum, it exhibits a dose-dependent inhibition of tyrosinase activity, achieving approximately 54.5% inhibition at 50 μg/mL. Additionally, Taraxinic acid demonstrates cytotoxic effects against melanoma cell lines A375 and HTB140 with an IC50 of 83.2 μM, and WM793 with an IC50 of 60.4 μM, indicating significant potential for applications in anticancer research.
Chemical Information
| Catalog Num | A78102 |
|---|---|
| M. Wt | 262.30 |
| Formula | C15H18O4 |
| Purity | >98% |
| Storage | at -20 °C 3 years (powder form); at -20 °C 6 months (Solution base) |
| CAS No. | 75911-33-0 |
| Synonyms | |
| SMILES | O=C(/C1=C\CC/C(C)=C/[C@@]([C@](CC1)([H])C2=C)([H])OC2=O)O |
Biological Activity
| Description | Taraxinic acid is a potent inhibitor of tyrosinase, an enzyme crucial for melanin biosynthesis. Derived from the roots of Taraxacum flavostylum and Taraxacum lucidum, it exhibits a dose-dependent inhibition of tyrosinase activity, achieving approximately 54.5% inhibition at 50 μg/mL. Additionally, Taraxinic acid demonstrates cytotoxic effects against melanoma cell lines A375 and HTB140 with an IC50 of 83.2 μM, and WM793 with an IC50 of 60.4 μM, indicating significant potential for applications in anticancer research. |
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RETURN POLICY
Adooq’s Unconditional Return Policy ensures a smooth online shopping experience for our customers. If you are in any way unsatisfied with your purchase, you may return any item(s) within 7 days of receiving it. In the event of product quality issues, either protocol related or product related problems, you may return any item(s) within 365 days from the original purchase date. Please follow the instructions below when returning products.
Adooq’s Unconditional Return Policy ensures a smooth online shopping experience for our customers. If you are in any way unsatisfied with your purchase, you may return any item(s) within 7 days of receiving it. In the event of product quality issues, either protocol related or product related problems, you may return any item(s) within 365 days from the original purchase date. Please follow the instructions below when returning products.
SHIPPING AND STORAGE
Adooq products are transported at room temperature. If you receive the product at room temperature, please rest assured, the Adooq Quality Inspection Department has conducted experiments to verify that the normal temperature placement of one month will not affect the biological activity of powder products. After collecting, please store the product according to the requirements described in the datasheet. Most Adooq products are stable under the recommended conditions.
Adooq products are transported at room temperature. If you receive the product at room temperature, please rest assured, the Adooq Quality Inspection Department has conducted experiments to verify that the normal temperature placement of one month will not affect the biological activity of powder products. After collecting, please store the product according to the requirements described in the datasheet. Most Adooq products are stable under the recommended conditions.
