Product Data Sheet

Luvadaxistat

Catalog No. A78128

main product photo
Luvadaxistat is a highly selective and potent inhibitor of D-amino acid oxidase (DAAO), demonstrating an IC50 value of 14 nM in the inhibition of oxidative deamination of D-serine. This compound significantly elevates D-serine concentrations in various biological matrices, including the rodent brain, plasma, and cerebrospinal fluid. Luvadaxistat holds promise as a valuable tool for research into schizophrenia and related neurobiological disorders.
Chemical Information
Catalog NumA78128
M. Wt284.23
FormulaC13H11F3N2O2
Purity>98%
Storageat -20 °C 3 years (powder form); at -20 °C 6 months (Solution base)
CAS No.1425511-32-5
SynonymsTAK-831
SMILESO=C1C(O)=CC(CCC2=CC=C(C(F)(F)F)C=C2)=NN1
Biological Activity
DescriptionLuvadaxistat is a highly selective and potent inhibitor of D-amino acid oxidase (DAAO), demonstrating an IC50 value of 14 nM in the inhibition of oxidative deamination of D-serine. This compound significantly elevates D-serine concentrations in various biological matrices, including the rodent brain, plasma, and cerebrospinal fluid. Luvadaxistat holds promise as a valuable tool for research into schizophrenia and related neurobiological disorders.
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SHIPPING AND STORAGE
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