Product Data Sheet

Tigulixostat

Catalog No. A78130

main product photo
Tigulixostat is a selective xanthine oxidase inhibitor with potent activity, demonstrating IC50 values of 0.003 µM in bovine milk and 0.073 µM in rat plasma. This compound effectively lowers serum uric acid levels and is utilized in research focusing on gout and hyperuricemia. Its oral bioavailability and targeted mechanism make it a valuable tool in studying these conditions.
Chemical Information
Catalog NumA78130
M. Wt294.31
FormulaC16H14N4O2
Purity>98%
Storageat -20 °C 3 years (powder form); at -20 °C 6 months (Solution base)
CAS No.1287766-55-5
SynonymsLC350189
SMILESN#CC1=CN(C(C)C)C2=C1C=C(N3N=CC(C(O)=O)=C3)C=C2
Biological Activity
DescriptionTigulixostat is a selective xanthine oxidase inhibitor with potent activity, demonstrating IC50 values of 0.003 µM in bovine milk and 0.073 µM in rat plasma. This compound effectively lowers serum uric acid levels and is utilized in research focusing on gout and hyperuricemia. Its oral bioavailability and targeted mechanism make it a valuable tool in studying these conditions.
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