Product Data Sheet
Xanthine oxidase-IN-5
Catalog No. A78155
Xanthine oxidase-IN-5 is a potent and orally active inhibitor of xanthine oxidase (XO), exhibiting an IC50 value of 0.70 μM. This compound demonstrates favorable ligand efficiency (LE) and lipophilic ligand efficiency (LLE) values of 0.33 and 3.41, respectively. Xanthine oxidase-IN-5 has shown significant hypouricemic effects in hyperuricemic rat models, making it a valuable tool for research into conditions related to elevated uric acid levels.
Chemical Information
| Catalog Num | A78155 |
|---|---|
| M. Wt | 341.34 |
| Formula | C18H16FN3O3 |
| Purity | >98% |
| Storage | at -20 °C 3 years (powder form); at -20 °C 6 months (Solution base) |
| CAS No. | 2276711-87-4 |
| Synonyms | |
| SMILES | O=CC1=CC(F)=CC=C1OCC2=CN(CC3=CC=CC(OC)=C3)N=N2 |
Biological Activity
| Description | Xanthine oxidase-IN-5 is a potent and orally active inhibitor of xanthine oxidase (XO), exhibiting an IC50 value of 0.70 μM. This compound demonstrates favorable ligand efficiency (LE) and lipophilic ligand efficiency (LLE) values of 0.33 and 3.41, respectively. Xanthine oxidase-IN-5 has shown significant hypouricemic effects in hyperuricemic rat models, making it a valuable tool for research into conditions related to elevated uric acid levels. |
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RETURN POLICY
Adooq’s Unconditional Return Policy ensures a smooth online shopping experience for our customers. If you are in any way unsatisfied with your purchase, you may return any item(s) within 7 days of receiving it. In the event of product quality issues, either protocol related or product related problems, you may return any item(s) within 365 days from the original purchase date. Please follow the instructions below when returning products.
Adooq’s Unconditional Return Policy ensures a smooth online shopping experience for our customers. If you are in any way unsatisfied with your purchase, you may return any item(s) within 7 days of receiving it. In the event of product quality issues, either protocol related or product related problems, you may return any item(s) within 365 days from the original purchase date. Please follow the instructions below when returning products.
SHIPPING AND STORAGE
Adooq products are transported at room temperature. If you receive the product at room temperature, please rest assured, the Adooq Quality Inspection Department has conducted experiments to verify that the normal temperature placement of one month will not affect the biological activity of powder products. After collecting, please store the product according to the requirements described in the datasheet. Most Adooq products are stable under the recommended conditions.
Adooq products are transported at room temperature. If you receive the product at room temperature, please rest assured, the Adooq Quality Inspection Department has conducted experiments to verify that the normal temperature placement of one month will not affect the biological activity of powder products. After collecting, please store the product according to the requirements described in the datasheet. Most Adooq products are stable under the recommended conditions.
