Product Data Sheet

Xanthine oxidase-IN-17

Catalog No. A78157

main product photo
Xanthine oxidase-IN-17 is a selective inhibitor of xanthine oxidase (XOD), demonstrating an IC50 of 298 nM and a Ki of 167 nM. By inhibiting XOD, it effectively reduces the generation of superoxide radicals and decreases uric acid production. This compound exhibits no cytotoxic effects on AML-12 hepatocyte cells and is valuable for research addressing hyperuricemia and gout.
Chemical Information
Catalog NumA78157
M. Wt284.31
FormulaC17H16O4
Purity>98%
Storageat -20 °C 3 years (powder form); at -20 °C 6 months (Solution base)
CAS No.185522-92-3
Synonyms
SMILESCOC1=CC=C(C(/C=C/C2=CC=C(O)C=C2)=O)C(OC)=C1
Biological Activity
DescriptionXanthine oxidase-IN-17 is a selective inhibitor of xanthine oxidase (XOD), demonstrating an IC50 of 298 nM and a Ki of 167 nM. By inhibiting XOD, it effectively reduces the generation of superoxide radicals and decreases uric acid production. This compound exhibits no cytotoxic effects on AML-12 hepatocyte cells and is valuable for research addressing hyperuricemia and gout.
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