Product Data Sheet

TAN-1030A

Catalog No. A78190

main product photo
TAN-1030A is an indolocarbazole alkaloid that functions as a macrophage-activating agent. It induces morphological changes in murine macrophage cell lines, such as Mm 1, and enhances their phagocytic activity, Fc gamma receptor expression, and β-glucuronidase activity in both Mm 1 and J774A.1 cell lines. TAN-1030A can effectively activate macrophage functions in in vivo models, making it a valuable tool for studying immune responses and macrophage biology.
Chemical Information
Catalog NumA78190
M. Wt466.49
FormulaC27H22N4O4
Purity>98%
Storageat -20 °C 3 years (powder form); at -20 °C 6 months (Solution base)
CAS No.126221-76-9
Synonyms
SMILESC[C@]12N3C4=C(C5=CC=CC=C53)C(CNC6=O)=C6C7=C4N([C@](C/C([C@H]2OC)=N/O)([H])O1)C8=CC=CC=C78
Biological Activity
DescriptionTAN-1030A is an indolocarbazole alkaloid that functions as a macrophage-activating agent. It induces morphological changes in murine macrophage cell lines, such as Mm 1, and enhances their phagocytic activity, Fc gamma receptor expression, and β-glucuronidase activity in both Mm 1 and J774A.1 cell lines. TAN-1030A can effectively activate macrophage functions in in vivo models, making it a valuable tool for studying immune responses and macrophage biology.
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