Product Data Sheet

BMS-911172

Catalog No. A78204

main product photo
BMS-911172 is an inhibitor of adaptor-associated kinase 1 (AAK1), exhibiting an IC50 value of 35 nM. This compound is primarily used in research focused on modulating clathrin-mediated endocytosis and exploring the role of AAK1 in cellular processes. Its ability to selectively inhibit AAK1 makes it a valuable tool for investigating signaling pathways related to receptor internalization and trafficking.
Chemical Information
Catalog NumA78204
M. Wt339.34
FormulaC16H19F2N3O3
Purity>98%
Storageat -20 °C 3 years (powder form); at -20 °C 6 months (Solution base)
CAS No.1644248-18-9
Synonyms
SMILESN[C@@H](C(NC1=CC=C(C(OC(F)F)=C1)C2=CN=CO2)=O)CC(C)C
Biological Activity
DescriptionBMS-911172 is an inhibitor of adaptor-associated kinase 1 (AAK1), exhibiting an IC50 value of 35 nM. This compound is primarily used in research focused on modulating clathrin-mediated endocytosis and exploring the role of AAK1 in cellular processes. Its ability to selectively inhibit AAK1 makes it a valuable tool for investigating signaling pathways related to receptor internalization and trafficking.
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