Product Data Sheet
GAD65 (524-543)
Catalog No. A78224
GAD65 (524-543) is a bioactive peptide derived from the glutamic acid decarboxylase 65 protein. This peptide fragment plays a crucial role in eliciting proliferative T cell responses in the non-obese diabetic (NOD) mouse model of autoimmune diabetes. It serves as a selective stimulus for the diabetogenic T cell clone BDC2.5, enhancing the susceptibility of NOD mice to type 1 diabetes when immunized with GAD65 (524-543). This reagent is valuable for research into T cell activation, autoimmune diabetes mechanisms, and potential therapeutic targets.
Chemical Information
| Catalog Num | A78224 |
|---|---|
| M. Wt | 2238.67 |
| Formula | C97H168N28O28S2 |
| Purity | >98% |
| Storage | at -20 °C 3 years (powder form); at -20 °C 6 months (Solution base) |
| CAS No. | 152468-44-5 |
| Synonyms | |
| SMILES | C(N[C@H](C(N[C@H](C(N[C@H](C(N[C@H](C(N[C@H](C(N[C@H](C(N[C@H](C(N[C@H](C(N[C@@H](CC1=CC=C(O)C=C1)C(NCC(N[C@H](C(N[C@@H]([C@@H](C)O)C(O)=O)=O)[C@@H](C)O)=O)=O)=O)CCC(O)=O)=O)CCSC)=O)CCSC)=O)CCCNC(=N)N)=O)C)=O)CCCCN)=O)[C@H](CC)C)=O)C(C)C)(=O)[C@H]2N(C([C@@H](NC([C@@H](NC([C@@H](NC([C@@H](NC([C@@H](NC([C@H](CCCNC(=N)N)NC([C@H](CO)N)=O)=O)CC(C)C)=O)CO)=O)CCCCN)=O)C(C)C)=O)C)=O)CCC2 |
Biological Activity
| Description | GAD65 (524-543) is a bioactive peptide derived from the glutamic acid decarboxylase 65 protein. This peptide fragment plays a crucial role in eliciting proliferative T cell responses in the non-obese diabetic (NOD) mouse model of autoimmune diabetes. It serves as a selective stimulus for the diabetogenic T cell clone BDC2.5, enhancing the susceptibility of NOD mice to type 1 diabetes when immunized with GAD65 (524-543). This reagent is valuable for research into T cell activation, autoimmune diabetes mechanisms, and potential therapeutic targets. |
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RETURN POLICY
Adooq’s Unconditional Return Policy ensures a smooth online shopping experience for our customers. If you are in any way unsatisfied with your purchase, you may return any item(s) within 7 days of receiving it. In the event of product quality issues, either protocol related or product related problems, you may return any item(s) within 365 days from the original purchase date. Please follow the instructions below when returning products.
Adooq’s Unconditional Return Policy ensures a smooth online shopping experience for our customers. If you are in any way unsatisfied with your purchase, you may return any item(s) within 7 days of receiving it. In the event of product quality issues, either protocol related or product related problems, you may return any item(s) within 365 days from the original purchase date. Please follow the instructions below when returning products.
SHIPPING AND STORAGE
Adooq products are transported at room temperature. If you receive the product at room temperature, please rest assured, the Adooq Quality Inspection Department has conducted experiments to verify that the normal temperature placement of one month will not affect the biological activity of powder products. After collecting, please store the product according to the requirements described in the datasheet. Most Adooq products are stable under the recommended conditions.
Adooq products are transported at room temperature. If you receive the product at room temperature, please rest assured, the Adooq Quality Inspection Department has conducted experiments to verify that the normal temperature placement of one month will not affect the biological activity of powder products. After collecting, please store the product according to the requirements described in the datasheet. Most Adooq products are stable under the recommended conditions.
