Product Data Sheet

Amyloid β-Protein (3-42)

Catalog No. A78269

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Amyloid β-Protein (3-42) is a precursor of pyroglutamate-modified Aβ, playing a critical role in the formation of amyloid plaques associated with Alzheimer's disease. This peptide contributes to the aggregation of Aβ(1-42), and its modified form, pEAβ(3-42), is known to accelerate Aβ(1-42) aggregation while inhibiting its nucleation processes. Research applications include studies on amyloid pathology and the mechanisms underlying Alzheimer's disease.
Chemical Information
Catalog NumA78269
M. Wt4327.87
FormulaC196H301N53O56S
Purity>98%
Storageat -20 °C 3 years (powder form); at -20 °C 6 months (Solution base)
CAS No.157884-74-7
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Biological Activity
DescriptionAmyloid β-Protein (3-42) is a precursor of pyroglutamate-modified Aβ, playing a critical role in the formation of amyloid plaques associated with Alzheimer's disease. This peptide contributes to the aggregation of Aβ(1-42), and its modified form, pEAβ(3-42), is known to accelerate Aβ(1-42) aggregation while inhibiting its nucleation processes. Research applications include studies on amyloid pathology and the mechanisms underlying Alzheimer's disease.
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