Product Data Sheet
h-FTAA
Catalog No. A78278
h-FTAA is a luminescent conjugated oligothiophene (LCO) probe that selectively targets amyloid protein aggregates, including Aβ plaques. This compound enables the differentiation of various aggregate conformations through fluorescence signal changes. Additionally, h-FTAA has been shown to reduce the neurotoxicity of Aβ1-42 and the Arctic mutant Aβ (AβArc), providing protection to SH-SY5Y neuroblastoma cells. Its application includes the dynamic tracking of Aβ plaque formation and maturation processes, making it valuable for research in neurodegenerative diseases.
Chemical Information
| Catalog Num | A78278 |
|---|---|
| M. Wt | 780.97 |
| Formula | C34H20O8S7 |
| Purity | >98% |
| Storage | at -20 °C 3 years (powder form); at -20 °C 6 months (Solution base) |
| CAS No. | 1352477-26-9 |
| Synonyms | |
| SMILES | O=C(C1=CC=C(C2=CC=C(C3=CC(CC(O)=O)=C(C4=CC=C(C5=C(CC(O)=O)C=C(C6=CC=C(C7=CC=C(C(O)=O)S7)S6)S5)S4)S3)S2)S1)O |
Biological Activity
| Description | h-FTAA is a luminescent conjugated oligothiophene (LCO) probe that selectively targets amyloid protein aggregates, including Aβ plaques. This compound enables the differentiation of various aggregate conformations through fluorescence signal changes. Additionally, h-FTAA has been shown to reduce the neurotoxicity of Aβ1-42 and the Arctic mutant Aβ (AβArc), providing protection to SH-SY5Y neuroblastoma cells. Its application includes the dynamic tracking of Aβ plaque formation and maturation processes, making it valuable for research in neurodegenerative diseases. |
|---|
RETURN POLICY
Adooq’s Unconditional Return Policy ensures a smooth online shopping experience for our customers. If you are in any way unsatisfied with your purchase, you may return any item(s) within 7 days of receiving it. In the event of product quality issues, either protocol related or product related problems, you may return any item(s) within 365 days from the original purchase date. Please follow the instructions below when returning products.
Adooq’s Unconditional Return Policy ensures a smooth online shopping experience for our customers. If you are in any way unsatisfied with your purchase, you may return any item(s) within 7 days of receiving it. In the event of product quality issues, either protocol related or product related problems, you may return any item(s) within 365 days from the original purchase date. Please follow the instructions below when returning products.
SHIPPING AND STORAGE
Adooq products are transported at room temperature. If you receive the product at room temperature, please rest assured, the Adooq Quality Inspection Department has conducted experiments to verify that the normal temperature placement of one month will not affect the biological activity of powder products. After collecting, please store the product according to the requirements described in the datasheet. Most Adooq products are stable under the recommended conditions.
Adooq products are transported at room temperature. If you receive the product at room temperature, please rest assured, the Adooq Quality Inspection Department has conducted experiments to verify that the normal temperature placement of one month will not affect the biological activity of powder products. After collecting, please store the product according to the requirements described in the datasheet. Most Adooq products are stable under the recommended conditions.
